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A comparison of six osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia

Shean Toh, Li; Lai, Pauline Siew Mei; Wu, David Bin-Chia; Bell, Brian G.; Dang, Cuu Phuong Linh; Low, Bee Yean; Wong, Kok Thong; Guglielmi, Giuseppe; Anderson, Claire

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Authors

Pauline Siew Mei Lai

David Bin-Chia Wu

BRIAN BELL BRIAN.BELL@NOTTINGHAM.AC.UK
Research Fellow

Cuu Phuong Linh Dang

Bee Yean Low

Kok Thong Wong

Giuseppe Guglielmi



Abstract

Objectives
To compare and assess the performance of 6 osteoporosis risk assessment tools for screening osteoporosis in Malaysian postmenopausal women.

Methods
Six osteoporosis risk assessments tools (the Simple Calculated Osteoporosis Risk Estimation [SCORE], the Osteoporosis Risk Assessment Instrument, the Age Bulk One or Never Estrogen, the body weight, the Malaysian Osteoporosis Screening Tool, and the Osteoporosis Self-Assessment Tool for Asians) were used to screen postmenopausal women who had not been previously diagnosed with osteoporosis/osteopenia. These women also underwent a dual-energy X-ray absorptiometry (DXA) scan to confirm the absence or presence of osteoporosis.

Results
A total of 164/224 participants were recruited (response rate, 73.2%), of which only 150/164 (91.5%) completed their DXA scan. Sixteen participants (10.7%) were found to have osteoporosis, whilst 65/150 (43.3%) were found to have osteopenia. Using precision-recall curves, the recall of the tools ranged from 0.50 to 1.00, whilst precision ranged from 0.04 to 0.14. The area under the curve (AUC) ranged from 0.027 to 0.161. The SCORE had the best balance between recall (1.00), precision (0.04–0.12), and AUC (0.072–0.161).

Conclusions
We found that the SCORE had the best balance between recall, precision, and AUC among the 6 screening tools that were compared among Malaysian postmenopausal women.

Citation

Shean Toh, L., Lai, P. S. M., Wu, D. B., Bell, B. G., Dang, C. P. L., Low, B. Y., …Anderson, C. (2019). A comparison of six osteoporosis risk assessment tools among postmenopausal women in Kuala Lumpur, Malaysia. Osteoporosis and Sarcopenia, 5(3), 87-93. https://doi.org/10.1016/j.afos.2019.09.001

Journal Article Type Article
Acceptance Date Sep 3, 2019
Online Publication Date Sep 11, 2019
Publication Date Sep 11, 2019
Deposit Date Oct 1, 2019
Publicly Available Date Mar 29, 2024
Journal Osteoporosis and Sarcopenia
Electronic ISSN 2405-5255
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 5
Issue 3
Pages 87-93
DOI https://doi.org/10.1016/j.afos.2019.09.001
Keywords Osteoporosis; Screening; Osteoporosis self-assessment tool for asians; Risk assessment; Performance comparison
Public URL https://nottingham-repository.worktribe.com/output/2473771
Publisher URL https://www.sciencedirect.com/science/article/pii/S2405525519300159

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