Sagnelli
Starch/Poly (Glycerol-Adipate) Nanocomposite Film as Novel Biocompatible Materials
Sagnelli; Cavanagh; Xu; Swainson; Blennow; Duncan; Taresco; Howdle
Authors
Cavanagh
Xu
Swainson
Blennow
Duncan
VINCENZO TARESCO VINCENZO.TARESCO@NOTTINGHAM.AC.UK
Nottingham Research Fellow
Prof. STEVE HOWDLE STEVE.HOWDLE@NOTTINGHAM.AC.UK
Professor of Chemistry
Abstract
Starch is one of the most abundant polysaccharides on the earth and it is the most important source of energy intake for humans. Thermoplastic starch (TPS) is also widely used for new bio-based materials. The blending of starch with other molecules may lead to new interesting biodegradable scaffolds to be exploited in food, medical, and pharmaceutical fields. In this work, we used native starch films as biopolymeric matrix carriers of chemo enzymatically-synthesized poly (glycerol-adipate) (PGA) nanoparticles (NPs) to produce a novel and biocompatible material. The prototype films had a crystallinity ranging from 4% to 7%. The intrinsic and thermo-mechanical properties of the composite showed that the incorporation of NPs in the starch films decreases the glass transition temperature. The utilization of these film prototypes as the basis for new biocompatible material showed promise, particularly because they have a very low or even zero cytotoxicity. Coumarin was used to monitor the distribution of the PGA NPs in the films and demonstrated a possible interaction between the two polymers. These novel hybrid nanocomposite films show great promise and could be used in the future as biodegradable and biocompatible platforms for the controlled release of amphiphilic and hydrophobic active ingredients.
Citation
Sagnelli, Cavanagh, Xu, Swainson, Blennow, Duncan, …Howdle. (2019). Starch/Poly (Glycerol-Adipate) Nanocomposite Film as Novel Biocompatible Materials. Coatings, 9(8), Article 482. https://doi.org/10.3390/coatings9080482
Journal Article Type | Article |
---|---|
Acceptance Date | Jul 27, 2019 |
Online Publication Date | Jul 30, 2019 |
Publication Date | 2019-08 |
Deposit Date | Aug 14, 2019 |
Publicly Available Date | Aug 15, 2019 |
Journal | Coatings |
Electronic ISSN | 2079-6412 |
Publisher | MDPI |
Peer Reviewed | Peer Reviewed |
Volume | 9 |
Issue | 8 |
Article Number | 482 |
DOI | https://doi.org/10.3390/coatings9080482 |
Public URL | https://nottingham-repository.worktribe.com/output/2430554 |
Publisher URL | https://www.mdpi.com/2079-6412/9/8/482 |
Contract Date | Aug 14, 2019 |
Files
SHowdle Starch Poly (Glycerol Adipate) Nanocomposite Film
(3.4 Mb)
PDF
Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
You might also like
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: discovery-access-systems@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search