Early-Stage Breast Cancer in Older Adults

Cheung, Kwok-Leung; Livi, Lorenzo; Brain, Etienne

Abstract

Breast cancer is the most common cancer afflicting women worldwide. Its incidence peaks around 70, while mortality increases greatly after 75 years old. Given the competing risks on mortality with multimorbidities, geriatric assessment is a leitmotiv and is considered as the mandatory and non-opposable strategy to use for personalizing treatment. This is especially true for strategies used in early-stage breast cancer since benefits are expected to come with long follow-up.

Therefore treatment choice needs careful assessment of the benefit/risk balance and guidance according to a general health status assessment, in order to avoid jeopardizing functional status and quality of life.

This chapter will highlight the unmet clinical needs, future opportunities and adjusted strategies for local treatments (surgery and radiotherapy), and systemic treatments (chemotherapy, endocrine therapy, and anti-HER2 treatment) in the older patients with early-stage breast cancer.

Citation

Cheung, K., Livi, L., & Brain, E. (2019). Early-Stage Breast Cancer in Older Adults. In M. Extermann (Ed.), Geriatric Oncology, 1-10. Springer. doi:10.1007/978-3-319-44870-1_33-1

• Acceptance Date: Jun 14, 2019
• Online Publication Date: Aug 8, 2019
• Publication Date: 2019
• Deposit Date: Aug 14, 2019
• Publicly Available Date: Aug 9, 2021
• Journal: Geriatric Oncology
• Publisher: Springer
• Pages: 1-10
• Book Title: Geriatric Oncology
• DOI: https://doi.org/10.1007/978-3-319-44870-1_33-1
• Public URL: https://nottingham-repository.worktribe.com/output/2427390
• Publisher URL: https://link.springer.com/referenceworkentry/10.1007%2F978-3-319-44870-1_33-1
• Additional Information: Received: 8 April 2019, 00:00:00; Accepted: 14 June 2019, 00:00:00; First Online: 8 August 2019