Virtual Instrumentation for Electrochemical Biosensor Applications

Madasamy, Thangamuthu; Pandiaraj, Manickam; Balamurugan, Murugesan; Santharaman, Paulraj; Venkatesh, Arun; Vairamani, Kanagavel; Robson Benjamin, Alby; Karunakaran, Chandran

Abstract

Virtual instrumentation (VI) is defined as an instrument whose general function and capabilities are determined in software. Especially, graphical user interface (GUI) software LabVIEW (Laboratory Virtual Instrumentation Engineering Workbench) is ideal for creating low cost and user friendly virtual instruments. In recent times, development of VI for electroanalytical applications are highly focused since the existing commercial instruments involve high cost and pre-defined hardware components restricting the users for the field study. Meticulously, highly flexible and hand held VI is needed for the detection of clinically important biomarkers using electrochemical biosensor technique. Therefore, in this article, we have attempted to explore the development of VI for the biosensor applications. In this context, a virtual instrument made up of home-made potentiostat connected with data acquisition system (NI MyDAQ) processed by GUI software performing cyclic voltammetry is discussed for the biosensing of nitric oxide and its metabolites and immunosensing of cytochrome c. The electroanalytical parameters viz. detection limit, linearity and sensitivity of the biosensors observed using VI are comparable with the results obtained using standard commercial instrument. But, in terms of cost, size and flexibility, VI is superior to the standard instrument for the biosensor applications and also enhancing the skill of the operator.

Citation

Madasamy, T., Pandiaraj, M., Balamurugan, M., Santharaman, P., Venkatesh, A., Vairamani, K., Robson Benjamin, A., & Karunakaran, C. (2017). Virtual Instrumentation for Electrochemical Biosensor Applications. Sensor Letters, 15(1), 1-10. https://doi.org/10.1166/sl.2017.3762

• Journal Article Type: Article
• Online Publication Date: Jan 1, 2017
• Publication Date: 2017-01
• Deposit Date: Jul 31, 2023
• Journal: Sensor Letters
• Print ISSN: 1546-198X
• Electronic ISSN: 1546-1971
• Publisher: American Scientific Publishers
• Peer Reviewed: Peer Reviewed
• Volume: 15
• Issue: 1
• Pages: 1-10
• DOI: https://doi.org/10.1166/sl.2017.3762
• Keywords: Electrical and Electronic Engineering; Atomic and Molecular Physics, and Optics
• Public URL: https://nottingham-repository.worktribe.com/output/23549822
• Publisher URL: https://www.ingentaconnect.com/content/asp/senlet/2017/00000015/00000001/art00001;jsessionid=1kno8nf4w67e.x-ic-live-03