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Virtual Instrumentation for Electrochemical Biosensor Applications

Madasamy, Thangamuthu; Pandiaraj, Manickam; Balamurugan, Murugesan; Santharaman, Paulraj; Venkatesh, Arun; Vairamani, Kanagavel; Robson Benjamin, Alby; Karunakaran, Chandran

Authors

Manickam Pandiaraj

Murugesan Balamurugan

Paulraj Santharaman

Arun Venkatesh

Kanagavel Vairamani

Alby Robson Benjamin

Chandran Karunakaran



Abstract

Virtual instrumentation (VI) is defined as an instrument whose general function and capabilities are determined in software. Especially, graphical user interface (GUI) software LabVIEW (Laboratory Virtual Instrumentation Engineering Workbench) is ideal for creating low cost and user friendly virtual instruments. In recent times, development of VI for electroanalytical applications are highly focused since the existing commercial instruments involve high cost and pre-defined hardware components restricting the users for the field study. Meticulously, highly flexible and hand held VI is needed for the detection of clinically important biomarkers using electrochemical biosensor technique. Therefore, in this article, we have attempted to explore the development of VI for the biosensor applications. In this context, a virtual instrument made up of home-made potentiostat connected with data acquisition system (NI MyDAQ) processed by GUI software performing cyclic voltammetry is discussed for the biosensing of nitric oxide and its metabolites and immunosensing of cytochrome c. The electroanalytical parameters viz. detection limit, linearity and sensitivity of the biosensors observed using VI are comparable with the results obtained using standard commercial instrument. But, in terms of cost, size and flexibility, VI is superior to the standard instrument for the biosensor applications and also enhancing the skill of the operator.

Citation

Madasamy, T., Pandiaraj, M., Balamurugan, M., Santharaman, P., Venkatesh, A., Vairamani, K., …Karunakaran, C. (2017). Virtual Instrumentation for Electrochemical Biosensor Applications. Sensor Letters, 15(1), 1-10. https://doi.org/10.1166/sl.2017.3762

Journal Article Type Article
Online Publication Date Jan 1, 2017
Publication Date 2017-01
Deposit Date Jul 31, 2023
Journal Sensor Letters
Print ISSN 1546-198X
Electronic ISSN 1546-1971
Publisher American Scientific Publishers
Peer Reviewed Peer Reviewed
Volume 15
Issue 1
Pages 1-10
DOI https://doi.org/10.1166/sl.2017.3762
Keywords Electrical and Electronic Engineering; Atomic and Molecular Physics, and Optics
Public URL https://nottingham-repository.worktribe.com/output/23549822
Publisher URL https://www.ingentaconnect.com/content/asp/senlet/2017/00000015/00000001/art00001;jsessionid=1kno8nf4w67e.x-ic-live-03