Oncoplastic breast surgery in older women with primary breast cancer: a systematic review

Chia, Zoe; Lee, Rachel X N; Cardoso, Maria J; Cheung, Kwok Leung; Parks, Ruth M

Abstract

Oncoplastic procedures allow excision of larger breast tumours, or unfavourable tumour/breast ratio lesions while achieving a good cosmetic outcome. This increases the pool of patients eligible for breast conservation over mastectomy, reducing the need for more extensive surgery in older women and potentially improving their quality of life. Nonetheless, studies to date suggest a poor uptake of oncoplastic breast surgery in the older group. This review aimed to establish whether a disparity in uptake of oncoplastic breast surgery exists between older and younger women, and to explore the underlying reasons for this. A literature search was conducted on 17 January 2022 using MEDLINE and Embase. Eligible studies comprised full-text articles of patients who underwent oncoplastic breast surgery for primary invasive breast cancer, and included those aged at least 65 years. Ten published studies were identified. One study was ranked as providing level 2 evidence, and the remainder were level 3. A total of 567 women underwent oncoplastic breast surgery for primary breast cancer, of whom only 61 (10.8 per cent) were aged 65 years or older. None of the studies directly compared younger with older women, or explored the underlying factors contributing to this discrepancy in uptake. This review has demonstrated a lower uptake of oncoplastic breast surgery in older compared with younger women. Given the increasing number of older women living with breast cancer who may be eligible for breast-conserving surgery, further research into this area is required. [Abstract copyright: © The Author(s) 2023. Published by Oxford University Press on behalf of BJS Society Ltd.]

Citation

Chia, Z., Lee, R. X. N., Cardoso, M. J., Cheung, K. L., & Parks, R. M. (2023). Oncoplastic breast surgery in older women with primary breast cancer: a systematic review. British Journal of Surgery, 110(10), 1309-1315. https://doi.org/10.1093/bjs/znad161

• Journal Article Type: Article
• Acceptance Date: May 6, 2023
• Online Publication Date: Jun 13, 2023
• Publication Date: Jun 13, 2023
• Deposit Date: Jun 19, 2023
• Publicly Available Date: Jun 19, 2023
• Journal: British Journal of Surgery
• Print ISSN: 0007-1323
• Electronic ISSN: 1365-2168
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 110
• Issue: 10
• Pages: 1309-1315
• DOI: https://doi.org/10.1093/bjs/znad161
• Keywords: Surgery
• Public URL: https://nottingham-repository.worktribe.com/output/22145007
• Publisher URL: https://academic.oup.com/bjs/advance-article/doi/10.1093/bjs/znad161/7195194?login=false