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Feed thickeners in gastro-oesophageal reflux in infants

Kwok, T’ng Chang; Ojha, Shalini; Dorling, Jon


T’ng Chang Kwok

Clinical Associate Professor

Jon Dorling


Gastro-oesophageal reflux (GOR) is the involuntary retrograde passage of gastric contents into the oesophagus with or without regurgitation. This is a common physiological, self-limiting condition in healthy infants with a prevalence peaking at 3–4 months of age, occurring more than once a day in 50% of healthy infants. As infants achieve upright posture with neurodevelopment maturation and acquire a more solid diet with age, symptoms usually improve by 6 months old with resolution by 12–14 months old.1 Transient inappropriate relaxation of the lower oesophageal sphincter and delayed gastric emptying are common mechanisms leading to GOR.
This is further exaggerated in preterm infants who have shorter and immature oesophagus with non-peristaltic motility.

Journal Article Type Article
Publication Date Jun 27, 2018
Journal BMJ Paediatrics Open
Electronic ISSN 2399-9772
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 2
Issue 1
Pages e000262
APA6 Citation Kwok, T. C., Ojha, S., & Dorling, J. (2018). Feed thickeners in gastro-oesophageal reflux in infants. BMJ Paediatrics Open, 2(1), e000262.
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