R. Gill
Group-contribution approach to the behaviour of 2-phenyl-ethylamines in reversed-phase high-performance liquid chromatography
Gill, R.; Alexander, S. P.; Moffat, A. C.
Abstract
High-performance liquid chromatography retention data are reported for 2-phenylethylamine and 30 of its derivatives, including examples of CH3 OH, OCH3, COOH, NH2 and N-oxide substitution. An octadecyl-silica column was used with an eluent of 10% methanol containing an amine-phosphate buffer (pH 3.15) to limit the interference of the silica support with chromatographic retention. The effects of individual substituents on retention are quantified by using group-contribution values (τ) and are discussed with reference to the position of substitution and the intramolecular interactions with other groups. © 1981.
Citation
Gill, R., Alexander, S. P., & Moffat, A. C. (1981). Group-contribution approach to the behaviour of 2-phenyl-ethylamines in reversed-phase high-performance liquid chromatography. Journal of Chromatography A, 218(C), 639-646. https://doi.org/10.1016/S0021-9673%2800%2982089-0
Journal Article Type | Article |
---|---|
Online Publication Date | Nov 1, 2001 |
Publication Date | Nov 20, 1981 |
Deposit Date | Dec 3, 2022 |
Journal | Journal of Chromatography A |
Print ISSN | 0021-9673 |
Electronic ISSN | 1873-3778 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 218 |
Issue | C |
Pages | 639-646 |
DOI | https://doi.org/10.1016/S0021-9673%2800%2982089-0 |
Public URL | https://nottingham-repository.worktribe.com/output/14322357 |
Publisher URL | https://www.sciencedirect.com/science/article/abs/pii/S0021967300820890?via%3Dihub |
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