Neuromolecular Mechanisms of Cannabis Action

Adel, Yousra; Alexander, Stephen P.H.

Abstract

Most of our current understanding of the neuromolecular mechanisms of Cannabis action focusses on two plant cannabinoids, THC and CBD. THC acts primarily through presynaptic CB cannabinoid receptors to regulate neurotransmitter release in the brain, spinal cord and peripheral nerves. CBD action, on the other hand, is probably mediated through multiple molecular targets.

• Online Publication Date: Dec 18, 2020
• Publication Date: 2021
• Deposit Date: Dec 3, 2022
• Pages: 15-28
• Series Title: Advances in Experimental Medicine and Biology
• Series Number: 1264
• Series ISSN: 2214-8019
• Book Title: Cannabinoids and Neuropsychiatric Disorders
• ISBN: 9783030573683
• DOI: https://doi.org/10.1007/978-3-030-57369-0_2
• Public URL: https://nottingham-repository.worktribe.com/output/14321577
• Publisher URL: https://link.springer.com/chapter/10.1007/978-3-030-57369-0_2