Acute treatment of stroke (except thrombectomy)

Venturelli, Paula Mu�oz; Appleton, Jason P.; Anderson, Craig S.; Bath, Philip M.

Abstract

Purpose of Review: The management of patients with acute stroke has been revolutionized in recent years with the advent of new effective treatments. In this rapidly evolving field, we provide an update on the management of acute stroke excluding thrombectomy, looking to recent, ongoing, and future trials.
Recent Findings: Large definitive trials have provided insight into acute stroke care including broadening the therapeutic window for thrombolysis, alternatives to standard dose alteplase, the use of dual antiplatelet therapy early after minor ischemic stroke, and treating elevated blood pressure in intracerebral hemorrhage. Further ongoing and future trials are eagerly awaited in this ever-expanding area.
Summary: Although definitive trials have led to improvements in acute stroke care, there remains a need for further research to improve our understanding of pathophysiological mechanisms underlying different stroke types with the potential for treatments to be tailored to the individual.

Citation

Venturelli, P. M., Appleton, J. P., Anderson, C. S., & Bath, P. M. (2018). Acute treatment of stroke (except thrombectomy). Current Neurology and Neuroscience Reports, 18(11), Article 77. https://doi.org/10.1007/s11910-018-0883-x

• Journal Article Type: Article
• Acceptance Date: Aug 31, 2018
• Online Publication Date: Sep 18, 2018
• Publication Date: Nov 1, 2018
• Deposit Date: Nov 2, 2018
• Publicly Available Date: Sep 19, 2019
• Journal: Current Neurology and Neuroscience Reports
• Print ISSN: 1528-4042
• Electronic ISSN: 1534-6293
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 18
• Issue: 11
• Article Number: 77
• DOI: https://doi.org/10.1007/s11910-018-0883-x
• Keywords: General Neuroscience; Clinical Neurology
• Public URL: https://nottingham-repository.worktribe.com/output/1220767
• Publisher URL: https://link.springer.com/article/10.1007%2Fs11910-018-0883-x#Sec5
• Contract Date: Nov 2, 2018