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Acute treatment of stroke (except thrombectomy)

Venturelli, Paula Mu�oz; Appleton, Jason P.; Anderson, Craig S.; Bath, Philip M.


Paula Mu�oz Venturelli

Jason P. Appleton

Craig S. Anderson

Stroke Association Professor of Stroke Medicine


Purpose of Review: The management of patients with acute stroke has been revolutionized in recent years with the advent of new effective treatments. In this rapidly evolving field, we provide an update on the management of acute stroke excluding thrombectomy, looking to recent, ongoing, and future trials.
Recent Findings: Large definitive trials have provided insight into acute stroke care including broadening the therapeutic window for thrombolysis, alternatives to standard dose alteplase, the use of dual antiplatelet therapy early after minor ischemic stroke, and treating elevated blood pressure in intracerebral hemorrhage. Further ongoing and future trials are eagerly awaited in this ever-expanding area.
Summary: Although definitive trials have led to improvements in acute stroke care, there remains a need for further research to improve our understanding of pathophysiological mechanisms underlying different stroke types with the potential for treatments to be tailored to the individual.


Venturelli, P. M., Appleton, J. P., Anderson, C. S., & Bath, P. M. (2018). Acute treatment of stroke (except thrombectomy). Current Neurology and Neuroscience Reports, 18(11), doi:10.1007/s11910-018-0883-x

Journal Article Type Article
Acceptance Date Aug 31, 2018
Online Publication Date Sep 18, 2018
Publication Date Nov 1, 2018
Deposit Date Nov 2, 2018
Publicly Available Date Sep 19, 2019
Journal Current Neurology and Neuroscience Reports
Print ISSN 1528-4042
Electronic ISSN 1534-6293
Publisher Springer Verlag
Peer Reviewed Peer Reviewed
Volume 18
Issue 11
Article Number 77
Keywords General Neuroscience; Clinical Neurology
Public URL
Publisher URL


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