Cost-effectiveness of interventions to control cardiovascular diseases and type 2 diabetes mellitus in South Asia: protocol for a systematic review

Singh, Kavita; Chandra Sekaran, Ambalam M; Bhaumik, Soumyadeep; Aisola, Malini; Chattopadhyay, Kaushik; Gamage, Anuji U; de Silva, Padmal; Selvaraj, Sakthivel; Roy, Ambuj; Prabhakaran, Dorairaj; Tandon, Nikhil

Abstract

Introduction: While a number of strategies are being implemented to control cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM), the cost-effectiveness of these in the South Asian context has not been systematically evaluated. We aim to systematically review the economic (cost-effectiveness) evidence available on the individual-, group- and population-level interventions for control of CVD and T2DM in South Asia.
Methods and analysis: This review will consider all relevant economic evaluations, either conducted alongside randomised controlled trials or based on decision modelling estimates. These studies must include participants at risk of developing CVD/T2DM or with established disease in one or more of the South Asian countries (India, Bangladesh, Pakistan, Sri Lanka, Nepal, Maldives, Bhutan and Afghanistan). We will identify relevant papers by systematically searching all major databases and registries. Selected articles will be screened by two independent researchers. Methodological quality of the studies will be assessed using a modified Drummond and a Phillips checklist. Cochrane guidelines will be followed for bias assessment in the effectiveness studies.
Results: Results will be presented in line with the PRISMA (Preferred Reporting Items for Systematic review and Meta-analysis) checklist, and overall quality of evidence will be presented as per the GRADE (Grades of Recommendation, Assessment, Development and Evaluation) approach.
Ethics and dissemination: The study has received ethics approval from the All India Institute of Medical Sciences, New Delhi, India. The results of this review will provide policy-relevant recommendations for the uptake of cost-effectiveness evidence in prioritising decisions on essential chronic disease care packages for South Asia.

Citation

Singh, K., Chandra Sekaran, A. M., Bhaumik, S., Aisola, M., Chattopadhyay, K., Gamage, A. U., …Tandon, N. (2015). Cost-effectiveness of interventions to control cardiovascular diseases and type 2 diabetes mellitus in South Asia: protocol for a systematic review. BMJ Open, 5(3), Article e007205. https://doi.org/10.1136/bmjopen-2014-007205

• Journal Article Type: Article
• Acceptance Date: Feb 15, 2015
• Online Publication Date: Mar 10, 2015
• Publication Date: Mar 12, 2015
• Deposit Date: Apr 6, 2018
• Publicly Available Date: Feb 19, 2019
• Electronic ISSN: 2044-6055
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• Volume: 5
• Issue: 3
• Article Number: e007205
• DOI: https://doi.org/10.1136/bmjopen-2014-007205
• Public URL: https://nottingham-repository.worktribe.com/output/1120106
• Publisher URL: https://bmjopen.bmj.com/content/5/3/e007205
• PMID: 25757948