Skip to main content

Research Repository

Advanced Search

Audiological biomarkers of tinnitus in an older Portuguese population

Haider, Haúla F.; Ribeiro, Diogo; Ribeiro, Sara F.; Trigueiros, Nuno; Caria, Helena; Borrego, Luís; Pinto, Iola; Papoila, Ana L.; Hoare, Derek J.; Paço, João

Audiological biomarkers of tinnitus in an older Portuguese population Thumbnail


Authors

Haúla F. Haider

Diogo Ribeiro

Sara F. Ribeiro

Nuno Trigueiros

Helena Caria

Luís Borrego

Iola Pinto

Ana L. Papoila

DEREK HOARE derek.hoare@nottingham.ac.uk
Associate Professor in Hearing Sciences

João Paço



Abstract

Tinnitus is a phantom sound perceived in the absence of external acoustic stimulation. It is described in a variety of ways (e.g., buzzing, ringing, and roaring) and can be a single sound or a combination of different sounds. Our study evaluated associations between audiological parameters and the presence or severity of tinnitus, to improve tinnitus diagnosis, treatment, and prognosis. Our sample included 122 older participants (63 women and 59 men), aged 55–75 years from the Portuguese population, with or without sensory presbycusis and with or without tinnitus. All participants underwent a clinical evaluation through a structured interview, Ear, Nose, and Throat observation, and audiological evaluation (standard and extended audiometry, psychoacoustic tinnitus evaluation, auditory brainstem responses, and distortion product otoacoustic emissions). The Tinnitus Handicap Inventory was used to measure tinnitus symptom severity. Our data confirmed that the odds of developing tinnitus were significantly higher in the presence of noise exposure and hearing loss. Also, participants who had abrupt tinnitus onset and moderate or severe hyperacusis featured higher odds of at least moderate tinnitus. However, it was in the ABR that we obtained the most exciting and promising results, namely, in wave I, which was the common denominator in all findings. The increase in wave I amplitude is a protective factor to the odds of having tinnitus. Concerning the severity of tinnitus, the logistic regression model showed that for each unit of increase in the mean ratio V/I of ABR, the likelihood of having at least moderate tinnitus was 10% higher. Advancing knowledge concerning potential tinnitus audiological biomarkers can be crucial for the adequate diagnosis and treatment of tinnitus.

Citation

Haider, H. F., Ribeiro, D., Ribeiro, S. F., Trigueiros, N., Caria, H., Borrego, L., …Paço, J. (2022). Audiological biomarkers of tinnitus in an older Portuguese population. Frontiers in Aging Neuroscience, 14, Article 933117. https://doi.org/10.3389/fnagi.2022.933117

Journal Article Type Article
Acceptance Date Jul 28, 2022
Online Publication Date Aug 24, 2022
Publication Date Aug 24, 2022
Deposit Date Oct 17, 2022
Publicly Available Date Oct 18, 2022
Journal Frontiers in Aging Neuroscience
Electronic ISSN 1663-4365
Publisher Frontiers Media SA
Peer Reviewed Peer Reviewed
Volume 14
Article Number 933117
DOI https://doi.org/10.3389/fnagi.2022.933117
Keywords Cognitive Neuroscience; Aging
Public URL https://nottingham-repository.worktribe.com/output/11188360
Publisher URL https://www.frontiersin.org/articles/10.3389/fnagi.2022.933117/full

Files




You might also like



Downloadable Citations