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Anti-confocal versus confocal assessment of the middle ear simulated by Monte Carlo methods

Jung, David S.; Crowe, John A.; Birchall, John P.; Somekh, Michael G.; See, Chung W.

Authors

David S. Jung

John A. Crowe

John P. Birchall

Michael G. Somekh

Chung W. See



Abstract

The ability to monitor the inflammatory state of the middle ear mucosa would provide clinical utility. To enable spectral measurements on the mucosa whilst rejecting background signal from the eardrum an anti-confocal system is investigated. In contrast to the central pinhole in a confocal system the anti-confocal system uses a central stop to reject light from the in-focus plane, the eardrum, with all other light detected. Monte Carlo simulations of this system show an increase in detected signal and improved signal-to-background ratio compared to a conventional confocal set-up used to image the middle ear mucosa. System parameters are varied in the simulation and their influence on the level of background rejection are presented.

Journal Article Type Article
Publication Date Oct 1, 2015
Electronic ISSN 2156-7085
Publisher Optical Society of America
Peer Reviewed Peer Reviewed
Volume 6
Issue 10
Pages 3820-3825
APA6 Citation Jung, D. S., Crowe, J. A., Birchall, J. P., Somekh, M. G., & See, C. W. (2015). Anti-confocal versus confocal assessment of the middle ear simulated by Monte Carlo methods. Biomedical Optics Express, 6(10), 3820-3825. https://doi.org/10.1364/BOE.6.003820
DOI https://doi.org/10.1364/BOE.6.003820
Publisher URL https://www.osapublishing.org/boe/abstract.cfm?uri=boe-6-10-3820
PMID 00036223

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