Surveillance system for Healthcare-associated endophthalmitis at state level in a middle-income country: preliminary results

Luz, Reginaldo; Brandão de Assis, Denise; Madalosso, Geraldine; Timmons, Stephen; Padoveze, Maria Clara

Abstract

Purpose: To describe the implementation process and the preliminary results of a surveillance system for healthcare-associated endophthalmitis. Methods: This is a case study of the implementation of a surveillance system for healthcare-associated endophthalmitis. The system for healthcare-associated endophthalmitis is a structured system that enables surveillance of cases of healthcare-associated endophthalmitis after intraocular procedures, developed and coordinated by the Division of Hospital Infection at the State Health Department, São Paulo, Brazil. The implementation process included a pilot phase, followed by a scaling-up phase. Data were reported monthly to the Division of Hospital Infection by participating healthcare facilities that performed intraocular procedures in the state of São Paulo, Brazil, from September 2017 to December 2019. Results: Among the 1,483 eligible healthcare facilities, 175 engaged in the study (participation rate of 11.8%), reporting 222,728 intraocular procedures performed, of which 164,207 were cataract surgery and 58,521 were intravitreal injections. The overall incidence rate of endophthalmitis was reported to be 0.05% (n=105; 80 cases after cataract surgery and 25 cases after intravitreal injections). The incidence rates for healthcare facilities ranged from 0.02% to 4.55%. Most cases were caused by gram-positive bacteria, mainly Staphylococcus spp. In 36 (46.2%) of the cases, there was no bacterial growth; no sample was collected in 28 (26.7%) cases. This system for healthcare-associated endophthalmitis enabled the identification of an outbreak of four cases of endophthalmitis after intravitreal injections. Conclusion: The system for healthcare-associated endophthalmitis proved to be operationally viable and efficient for monitoring cases of endophthalmitis at the state level.

Citation

Luz, R., Brandão de Assis, D., Madalosso, G., Timmons, S., & Padoveze, M. C. (2023). Surveillance system for Healthcare-associated endophthalmitis at state level in a middle-income country: preliminary results. Arquivos Brasileiros de Oftalmologia, 87(4), Article e2022-0181. https://doi.org/10.5935/0004-2749.2022-0181

• Journal Article Type: Article
• Acceptance Date: Sep 7, 2022
• Publication Date: 2023
• Deposit Date: Sep 9, 2022
• Publicly Available Date: Dec 31, 2023
• Journal: Arquivos Brasileiros de Oftalmologia
• Print ISSN: 0004-2749
• Electronic ISSN: 1678-2925
• Peer Reviewed: Peer Reviewed
• Volume: 87
• Issue: 4
• Article Number: e2022-0181
• DOI: https://doi.org/10.5935/0004-2749.2022-0181
• Keywords: Epidemiological monitoring; Endophthalmitis; Delivery of healthcare; Health surveys; Ophthalmologic surgical procedures
• Public URL: https://nottingham-repository.worktribe.com/output/10919743
• Related Public URLs: https://www.scielo.br/j/abo/a/TTwqQDJxRpy87VnMGB8DRys/?format=pdf&lang=en