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Translational challenges and opportunities in biofilm science: a BRIEF for the future

Highmore, C. J.; Melaugh, G.; Morris, R. J.; Parker, J.; Direito, S. O. L.; Romero, M.; Soukarieh, F.; Robertson, S. N.; Bamford, N. C.

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Authors

C. J. Highmore

G. Melaugh

R. J. Morris

J. Parker

S. O. L. Direito

N. C. Bamford



Abstract

Biofilms are increasingly recognised as a critical global issue in a multitude of industries impacting health, food and water security, marine sector, and industrial processes resulting in estimated economic cost of $5 trillion USD annually. A major barrier to the translation of biofilm science is the gap between industrial practices and academic research across the biofilms field. Therefore, there is an urgent need for biofilm research to notice and react to industrially relevant issues to achieve transferable outputs. Regulatory frameworks necessarily bridge gaps between different players, but require a clear, science-driven non-biased underpinning to successfully translate research. Here we introduce a 2-dimensional framework, termed the Biofilm Research-Industrial Engagement Framework (BRIEF) for classifying existing biofilm technologies according to their level of scientific insight, including the understanding of the underlying biofilm system, and their industrial utility accounting for current industrial practices. We evidence the BRIEF with three case studies of biofilm science across healthcare, food & agriculture, and wastewater sectors highlighting the multifaceted issues around the effective translation of biofilm research. Based on these studies, we introduce some advisory guidelines to enhance the translational impact of future research.

Citation

Highmore, C. J., Melaugh, G., Morris, R. J., Parker, J., Direito, S. O. L., Romero, M., …Bamford, N. C. (2022). Translational challenges and opportunities in biofilm science: a BRIEF for the future. npj Biofilms and Microbiomes, 8, Article 68. https://doi.org/10.1038/s41522-022-00327-7

Journal Article Type Article
Acceptance Date Aug 4, 2022
Online Publication Date Aug 29, 2022
Publication Date Aug 29, 2022
Deposit Date Oct 21, 2022
Publicly Available Date Oct 21, 2022
Journal npj Biofilms and Microbiomes
Electronic ISSN 2055-5008
Publisher Springer Science and Business Media LLC
Peer Reviewed Peer Reviewed
Volume 8
Article Number 68
DOI https://doi.org/10.1038/s41522-022-00327-7
Keywords Applied Microbiology and Biotechnology; Microbiology; Biotechnology
Public URL https://nottingham-repository.worktribe.com/output/10907022
Publisher URL https://www.nature.com/articles/s41522-022-00327-7

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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/

Copyright Statement
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.




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