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Photothermal conversion and transfer in photothermal therapy: From macroscale to nanoscale

Ren, Yatao; Yan, Yuying; Qi, Hong


Yatao Ren

Professor of Thermofluids Engineering

Hong Qi


Photothermal therapy (PTT) is a promising alternative therapy for benign or even malignant tumors. To improve the selective heating of tumor cells, target-specific photothermal conversion agents are often included, especially nanoparticles. Meanwhile, some indirect methods by manipulating the radiation and heat delivery are also adopted. Therefore, to gain a clear understanding of the mechanism, and to improve the controllability of PTT, a few issues need to be clarified, including bioheat and radiation transfer, localized and collective heating of nanoparticles, etc. In this review, we provide an introduction to the typical bioheat transfer and radiation transfer models along with the dynamic thermophysical properties of biological tissue. On this basis, we reviewed the most recent advances in the temperature control methods in PTT from macroscale to nanoscale. Most importantly, a comprehensive introduction of the localized and collective heating effects of nanoparticle clusters is provided to give a clear insight into the mechanism for PPT from the microscale and nanoscale point of view.


Ren, Y., Yan, Y., & Qi, H. (2022). Photothermal conversion and transfer in photothermal therapy: From macroscale to nanoscale. Advances in Colloid and Interface Science, 308, Article 102753.

Journal Article Type Article
Acceptance Date Aug 8, 2022
Online Publication Date Aug 22, 2022
Publication Date 2022-10
Deposit Date Jan 31, 2023
Publicly Available Date Feb 1, 2023
Journal Advances in Colloid and Interface Science
Print ISSN 0001-8686
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 308
Article Number 102753
Keywords Colloid and Surface Chemistry; Physical and Theoretical Chemistry; Surfaces and Interfaces
Public URL
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