A quadrivalent vaccine for human papillomavirus

Brown, C.; Gaston, K.

Abstract

Cervical cancer is responsible for at least 13,500 deaths a year in the European Union and more than 30 times that worldwide. DNA from a group of human papillomaviruses (HPVs) is found in virtually all cervical carcinoma cells, and these so-called high-risk HPV types are acknowledged to be a necessary cause of this disease. Vaccines that target these HPV types have the potential to dramatically reduce the incidence of cervical carcinoma. Low-risk HPV types cause genital warts, a common sexually transmitted disease, and vaccines that target these HPV types and the high-risk HPV types, are therefore particularly attractive. This review will focus on the potential of a new HPV vaccine that appears to offer protection against the most prevalent high- and low-risk HPV types and their associated diseases.

Citation

Brown, C., & Gaston, K. (2006). A quadrivalent vaccine for human papillomavirus. Drugs of today (Barcelona, Spain : 1998), 42(11), 703-709. https://doi.org/10.1358/dot.2006.42.11.1032056

• Journal Article Type: Article
• Acceptance Date: Jun 1, 2006
• Publication Date: 2006-11
• Deposit Date: Nov 1, 2018
• Journal: Drugs of Today
• Print ISSN: 1699-3993
• Peer Reviewed: Peer Reviewed
• Volume: 42
• Issue: 11
• Pages: 703-709
• DOI: https://doi.org/10.1358/dot.2006.42.11.1032056
• Public URL: https://nottingham-repository.worktribe.com/output/1037723
• Publisher URL: https://journals.prous.com/journals/servlet/xmlxsl/pk_journals.xml_summary_pr?p_JournalId=4&p_RefId=1032056&p_IsPs=N