Professor STEPHEN COOMBES STEPHEN.COOMBES@NOTTINGHAM.AC.UK
Professor of Applied Mathematics
Toward blueprints for network architecture, biophysical dynamics, and signal transduction
Coombes, Stephen; Doiron, Brent; Josic, Kresimir; Shea-Brown, Eric
Authors
Brent Doiron
Kresimir Josic
Eric Shea-Brown
Abstract
We review mathematical aspects of biophysical dynamics, signal transduction and network architecture that have been used to uncover functionally significant relations between the dynamics of single neurons and the networks they compose. We focus on examples that combine insights from these three areas to expand our understanding of systems neuroscience. These range from single neuron coding to models of decision making and electrosensory discrimination by networks and populations, as well as coincidence detection in pairs of dendrites and the dynamics of large networks of excitable dendritic spines. We conclude by describing some of the challenges that lie ahead as the applied mathematics community seeks to provide the tools that will ultimately underpin systems neuroscience.
Citation
Coombes, S., Doiron, B., Josic, K., & Shea-Brown, E. (2006). Toward blueprints for network architecture, biophysical dynamics, and signal transduction
Journal Article Type | Article |
---|---|
Publication Date | Sep 1, 2006 |
Deposit Date | Sep 18, 2006 |
Publicly Available Date | Oct 9, 2007 |
Peer Reviewed | Peer Reviewed |
Public URL | https://nottingham-repository.worktribe.com/output/1018212 |
Files
Royal_06TA1019.pdf
(411 Kb)
PDF
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