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Characterisation of a group of endogenous gammaretroviruses in the canine genome

Tarlinton, Rachael E.; Barfoot, Hannah K.R.; Allen, Ceri E.; Brown, Katherine; Gifford, Robert J.; Emes, Richard D.

Authors

Rachael E. Tarlinton

Hannah K.R. Barfoot

Ceri E. Allen

Katherine Brown

Robert J. Gifford

Richard D. Emes



Abstract

Bioinformatics were used to identify and characterise 39 pol, 34 gag and five env gammaretroviruses within the canine (Canis lupus familiaris) reference genome. These endogenous retroviruses are monophyletic to the Canidae, predate the divergence of dogs and foxes and are fixed in 20 canine breeds examined. They are transcribed in normal canine tissue but are unlikely to be replication competent in dogs.

Journal Article Type Article
Publication Date Apr 1, 2013
Journal Veterinary Journal
Print ISSN 1090-0233
Electronic ISSN 1090-0233
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 196
Issue 1
APA6 Citation Tarlinton, R. E., Barfoot, H. K., Allen, C. E., Brown, K., Gifford, R. J., & Emes, R. D. (2013). Characterisation of a group of endogenous gammaretroviruses in the canine genome. Veterinary Journal, 196(1), doi:10.1016/j.tvjl.2012.08.011
DOI https://doi.org/10.1016/j.tvjl.2012.08.011
Keywords Canine, Endogenous retroviruses, Gammaretroviruses
Publisher URL http://www.sciencedirect.com/science/article/pii/S1090023312003528
Copyright Statement Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0

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Copyright Statement
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0





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