Outputs (2)

Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas (2011)
Journal Article
Al-Ghamdi, S., Albasri, A., Cachat, J., Ibrahem, S., Muhammad, B. A., Jackson, D., Nateri, A. S., Kindle, K. B., & Ilyas, M. (2011). Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas. PLoS ONE, 6(6), Article e20919. https://doi.org/10.1371/journal.pone.0020919

CTEN/TNS4 is an oncogene in colorectal cancer (CRC) which enhances cell motility although the mechanism of Cten regulation is unknown. We found an association between high Cten expression and KRAS/BRAF mutation in a series of CRC cell lines (p = 0.03... Read More about Cten is targeted by Kras signalling to regulate cell motility in the colon and pancreas.

C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer (2008)
Journal Article
Albasri, A., Seth, R., Jackson, D., Benhasouna, A., Crook, S., Nateri, A. S., Chapman, R., & Ilyas, M. (2009). C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer. The Journal of Pathology, 218(1), 57-65. https://doi.org/10.1002/path.2508

The Tensin gene family encodes proteins thought to modulate integrin function. C-terminal Tensin-like (CTEN) is a member of the Tensin gene family which lacks the N-terminus actin-binding domain. Cten is reported to have both oncogenic and tumour-sup... Read More about C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer.