Identification and characterisation of a rare MTTP variant underlying hereditary non-alcoholic fatty liver disease
(2023)
Journal Article
Grove, J. I., Lo, P. C., Shrine, N., Barwell, J., Wain, L. V., Tobin, M. D., Salter, A. M., Borkar, A. N., Cuevas-Ocaña, S., Bennett, N., John, C., Ntalla, I., Jones, G. E., Neal, C. P., Thomas, M. G., Kuht, H., Gupta, P., Vemala, V. M., Grant, A., Adewoye, A. B., …Aithal, G. P. (2023). Identification and characterisation of a rare MTTP variant underlying hereditary non-alcoholic fatty liver disease. JHEP Reports, 5(8), Article 100764. https://doi.org/10.1016/j.jhepr.2023.100764
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a complex trait with an estimated prevalence of 25% globally. We aimed to identify the genetic variant underlying a four-generation family with progressive NAFLD leading to cirrhosis, de... Read More about Identification and characterisation of a rare MTTP variant underlying hereditary non-alcoholic fatty liver disease.