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Comparing GABA-dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-high-field MRI (2017)
Journal Article
Dyke, K., Pépés, S. E., Chen, C., Kim, S., Sigurdsson, H. P., Draper, A., Husain, M., Nachev, P., Gowland, P. A., Morris, P. G., & Jackson, S. R. (2017). Comparing GABA-dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-high-field MRI. NeuroImage, 152, 360-370. https://doi.org/10.1016/j.neuroimage.2017.03.011

Imbalances in glutamatergic (excitatory) and GABA (inhibitory) signalling within key brain networks are thought to underlie many brain and mental health disorders, and for this reason there is considerable interest in investigating how individual var... Read More about Comparing GABA-dependent physiological measures of inhibition with proton magnetic resonance spectroscopy measurement of GABA using ultra-high-field MRI.

Impact of a common genetic variation associated with putamen volume on neural mechanisms of ADHD (2017)
Journal Article
Xu, B., Jia, T., Macare, C., Banaschewski, T., Bokde, A. L., Bromberg, U., Büchel, C., Cattrell, A., Conrod, P. J., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P. A., Heinz, A., Ittermann, B., Martinot, J.-L., Martinot, M.-L. P., Nees, F., Orfanos, D. P., …Desrivières, S. (2017). Impact of a common genetic variation associated with putamen volume on neural mechanisms of ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 56(5), 436-444.e4. https://doi.org/10.1016/j.jaac.2017.02.009

Objective: In a recent genome-wide association study of subcortical brain volumes, we have identified common genetic variation at rs945270 as having the strongest effect on putamen volume, a brain measure linked to familial risk for attentiondeficit/... Read More about Impact of a common genetic variation associated with putamen volume on neural mechanisms of ADHD.

Image quality transfer and applications in diffusion MRI (2017)
Journal Article
Alexander, D. C., Zikic, D., Ghosh, A., Tanno, R., Wottschel, V., Zhang, J., Kaden, E., Dyrby, T. B., Sotiropoulos, S. N., Zhang, H., & Criminisi, A. (2017). Image quality transfer and applications in diffusion MRI. NeuroImage, 152, https://doi.org/10.1016/j.neuroimage.2017.02.089

This paper introduces a new computational imaging technique called image quality transfer (IQT). IQT uses machine learning to transfer the rich information available from one-off experimental medical imaging devices to the abundant but lower-quality... Read More about Image quality transfer and applications in diffusion MRI.

Abnormal task driven neural oscillations in multiple sclerosis: a visuomotor MEG study (2017)
Journal Article
Barratt, E. L., Tewarie, P. K., Clarke, M. A., Hall, E. L., Gowland, P. A., Morris, P. G., Francis, S. T., Evangelou, N., & Brookes, M. J. (2017). Abnormal task driven neural oscillations in multiple sclerosis: a visuomotor MEG study. Human Brain Mapping, 38(5), 2441-2453. https://doi.org/10.1002/hbm.23531

Multiple sclerosis (MS) is a debilitating disease commonly attributed to degradation of white matter myelin. Symptoms include fatigue, as well as problems associated with vision and movement. Although areas of demyelination in white matter are observ... Read More about Abnormal task driven neural oscillations in multiple sclerosis: a visuomotor MEG study.

Studying neuroanatomy using MRI (2017)
Journal Article
Lerch, J. P., van der Kouwe, A. J., Raznahan, A., Paus, T., Johansen-Berg, H., Miller, K. L., Smith, S. M., Fischl, B., & Sotiropoulos, S. N. (in press). Studying neuroanatomy using MRI. Nature Neuroscience, 20(3), https://doi.org/10.1038/nn.4501

The study of neuroanatomy using imaging enables key insights into how our brains function, are shaped by genes and environment, and change with development, aging, and disease. Developments in MRI acquisition, image processing, and data modelling hav... Read More about Studying neuroanatomy using MRI.

Using Raman spectroscopy to improve hyperpolarized noble gas production for clinical lung imaging techniques (2017)
Book Chapter
Birchall, J., Whiting, N., Skinner, J., Barlow, M. J., & Goodson, B. M. (2017). Using Raman spectroscopy to improve hyperpolarized noble gas production for clinical lung imaging techniques. In Raman spectroscopy and applications (247-268). InTech. https://doi.org/10.5772/65114

Spin-exchange optical pumping (SEOP) can be used to “hyperpolarize” 129Xe for human lung MRI. SEOP involves transfer of angular momentum from light to an alkali metal (Rb) vapor, and then onto 129Xe nuclear spins during collisions; collisions between... Read More about Using Raman spectroscopy to improve hyperpolarized noble gas production for clinical lung imaging techniques.

Surface-sensitive NMR detection of the solid electrolyte interphase layer on reduced graphene oxide (2017)
Journal Article
Leskes, M., Kim, G., Liu, T., Michan, A. L., Aussenac, F., Dorffer, P., Paul, S., & Grey, C. P. (2017). Surface-sensitive NMR detection of the solid electrolyte interphase layer on reduced graphene oxide. Journal of Physical Chemistry Letters, 8(5), https://doi.org/10.1021/acs.jpclett.6b02590

Forming a stable solid electrolyte interphase (SEI) is critical for rechargeable batteries’ performance and lifetime. Understanding its formation requires analytical techniques that provide molecular-level insight. Here, dynamic nuclear polarization... Read More about Surface-sensitive NMR detection of the solid electrolyte interphase layer on reduced graphene oxide.

Exploring structure and function of sensory cortex with 7 T MRI (2017)
Journal Article
Schluppeck, D., Sánchez-Panchuelo, R.-M., & Francis, S. T. (2018). Exploring structure and function of sensory cortex with 7 T MRI. NeuroImage, 164, https://doi.org/10.1016/j.neuroimage.2017.01.081

In this paper, we present an overview of 7 Tesla magnetic resonance imaging (MRI) studies of the detailed function and anatomy of sensory areas of the human brain. We discuss the motivation for the studies, with particular emphasis on increasing the... Read More about Exploring structure and function of sensory cortex with 7 T MRI.

Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion (2017)
Journal Article
Grant, C., Harrison, L., Hoad, C., Marciani, L., Cox, E., Buchanan, C., Costigan, C., Francis, S., Lai, K.-B., Szeto, C.-C., Gowland, P., & McIntyre, C. (2017). Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion. Peritoneal Dialysis International, 37(1), 111-115. https://doi.org/10.3747/pdi.2016.00079

Endotoxemia is common in advanced chronic kidney disease and is particularly severe in those receiving dialysis. In hemodialysis patients, translocation from the bowel occurs as a consequence of recurrent circulatory stress leading to a reduction in... Read More about Endotoxemia in peritoneal dialysis patients: a pilot study to examine the role of intestinal perfusion and congestion.

Nanoscale engineering of hybrid magnetite–carbon nanofibre materials for magnetic resonance imaging contrast agents (2017)
Journal Article
Metelkina, O. N., Lodge, R. W., Rudakovskaya, P. G., Gerasimov, V. M., Lucas, C. H., Grebennikov, I. S., Shchetinin, I. V., Savchenko, A. G., Pavlovskaya, G. E., Rance, G. A., del Carmen Gimenez-Lopez, M., Khlobystov, A. N., & Majouga, A. G. (2017). Nanoscale engineering of hybrid magnetite–carbon nanofibre materials for magnetic resonance imaging contrast agents. Journal of Materials Chemistry C, 5(8), 2167-2174. https://doi.org/10.1039/C6TC04141H

Magnetic nanomaterials show significant promise as contrast agents for magnetic resonance imaging (MRI). We have developed a new highly efficient one-step procedure for the synthesis of magnetically- functionalised hollow carbon nanofibres, where (i)... Read More about Nanoscale engineering of hybrid magnetite–carbon nanofibre materials for magnetic resonance imaging contrast agents.