Outputs (53)

An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography (2017)
Journal Article
Glover, P. M., Watkins, R. H., O’Neill, G. C., Ackerley, R. M., Sánchez-Panchuelo, R.-M., McGlone, F., Brookes, M. J., Wessberg, J., & Francis, S. T. (2017). An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography. Journal of Neuroscience Methods, 290, 69-78. https://doi.org/10.1016/j.jneumeth.2017.07.016

Background

Intra-neural microstimulation (INMS) is a technique that allows the precise delivery of low-current electrical pulses into human peripheral nerves. Single unit INMS can be used to stimulate individual afferent nerve fibres during micron... Read More about An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography.

Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson’s disease (2017)
Journal Article
Akram, H., Sotiropoulos, S. N., Jbabdi, S., Georgiev, D., Mahlknecht, P., Hyam, J., Foltynie, T., Limousin, P., De Vita, E., Jahanshahi, M., Hariz, M., Ashburner, J., Behrens, T., & Zrinzo, L. (2017). Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson’s disease. NeuroImage, 158, https://doi.org/10.1016/j.neuroimage.2017.07.012

Objectives
Firstly, to identify subthalamic region stimulation clusters that predict maximum improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and secondly, to map-out the cortical fingerprint, mediated by the hyperdire... Read More about Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson’s disease.

Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans (2017)
Journal Article
Fouragnan, E., Queirazza, F., Retzler, C., Mullinger, K. J., & Philiastides, M. G. (in press). Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans. Scientific Reports, 7, Article 4762. https://doi.org/10.1038/s41598-017-04507-w

Reward learning depends on accurate reward associations with potential choices. These associations can be attained with reinforcement learning mechanisms using a reward prediction error (RPE) signal (the difference between actual and expected rewards... Read More about Spatiotemporal neural characterization of prediction error valence and surprise during reward learning in humans.

Estimation of white matter fiber parameters from compressed multiresolution diffusion MRI using sparse Bayesian learning (2017)
Journal Article
Pisharady, P. K., Sotiropoulos, S. N., Duarte-Carvajalino, J. M., Sapiro, G., & Lenglet, C. (in press). Estimation of white matter fiber parameters from compressed multiresolution diffusion MRI using sparse Bayesian learning. NeuroImage, https://doi.org/10.1016/j.neuroimage.2017.06.052

We present a sparse Bayesian unmixing algorithm BusineX: Bayesian Unmixing for Sparse Inference-based Estimation of Fiber Crossings (X), for estimation of white matter fiber parameters from compressed (under-sampled) diffusion MRI (dMRI) data. Busine... Read More about Estimation of white matter fiber parameters from compressed multiresolution diffusion MRI using sparse Bayesian learning.

Improved tractography using asymmetric fibre orientation distributions (2017)
Journal Article
Bastiani, M., Cottaar, M., Dikranian, K., Ghosh, A., Zhang, H., Alexander, D. C., Behrens, T. E., Jbabdi, S., & Sotiropoulos, S. N. (2017). Improved tractography using asymmetric fibre orientation distributions. NeuroImage, 158, https://doi.org/10.1016/j.neuroimage.2017.06.050

Diffusion MRI allows us to make inferences on the structural organisation of the brain by mapping water diffusion to white matter microstructure. However, such a mapping is generally ill-defined; for instance, diffusion measurements are antipodally s... Read More about Improved tractography using asymmetric fibre orientation distributions.

Building connectomes using diffusion MRI: why, how and but (2017)
Journal Article
Sotiropoulos, S. N., & Zalesky, A. (in press). Building connectomes using diffusion MRI: why, how and but. NMR in Biomedicine, https://doi.org/10.1002/nbm.3752

Why has diffusion MRI become a principal modality for mapping connectomes in vivo? How do different image acquisition parameters, fiber tracking algorithms and other methodological choices affect connectome estimation? What are the main factors that... Read More about Building connectomes using diffusion MRI: why, how and but.

Imaging Pain Relief in Osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome (2017)
Journal Article
Reckziegel, D., Bailey, H., Cottam, W. J., Tench, C. R., Mahajan, R. P., Walsh, D. A., Knaggs, R., & Auer, D. P. (in press). Imaging Pain Relief in Osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome. BMJ Open, 7(6), Article e014013. https://doi.org/10.1136/bmjopen-2016-014013

Introduction: Osteoarthritis (OA) pain is a major cause of long-term disability and chronic pain in the adult population. One in five patients does not receive satisfactory pain relief, which reflects the complexity of chronic pain and the current la... Read More about Imaging Pain Relief in Osteoarthritis (IPRO): protocol of a double-blind randomised controlled mechanistic study assessing pain relief and prediction of duloxetine treatment outcome.

Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans (2017)
Journal Article
Murray, K., Hoad, C. L., Mudie, D. M., Wright, J., Heissam, K., Abrehart, N., Pritchard, S. E., Al Atwah, S., Gowland, P. A., Garnett, M. C., Amidon, G. E., Spiller, R. C., Amidon, G. L., & Marciani, L. (2017). Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans. Molecular Pharmaceutics, 14(8), 2629-2638. https://doi.org/10.1021/acs.molpharmaceut.7b00095

The rate and extent of drug dissolution and absorption from solid oral dosage forms is highly dependent on the volume of liquid in the gastrointestinal tract (GIT). However, little is known about the time course of GIT liquid volumes after drinking a... Read More about Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans.

Presence of time-dependent diffusion in the brachial plexus (2017)
Journal Article
Mahbub, Z. B., Peters, A. M., & Gowland, P. A. (2018). Presence of time-dependent diffusion in the brachial plexus. Magnetic Resonance in Medicine, 79(2), 789-795. https://doi.org/10.1002/mrm.26733

© 2017 International Society for Magnetic Resonance in Medicine Purpose: This work describes the development of a method to measure the variation of apparent diffusion coefficient (ADC) with diffusion time (Δ) in the brachial plexus, as a potential m... Read More about Presence of time-dependent diffusion in the brachial plexus.

Psychosocial stress and brain function in adolescent psychopathology (2017)
Journal Article
Quinlan, E. B., Cattrell, A., Jia, T., Artiges, E., Banaschewski, T., Barker, G., Bokde, A. L., Bromberg, U., Büchel, C., Brühl, R., Conrod, P. J., Desrivières, S., Flor, H., Frouin, V., Gallinat, J., Garavan, H., Gowland, P. A., Heinz, A., Nees, F., Paillère-Martinot, M.-L., …Schumann, G. (2017). Psychosocial stress and brain function in adolescent psychopathology. American Journal of Psychiatry, 174(8), 785-794. https://doi.org/10.1176/appi.ajp.2017.16040464

Objective: To explore how conduct, hyperactivity/inattention, and emotional symptoms are associated with neural reactivity to social-emotional stimuli, and the extent to which psychosocial stress modulates these relationships.
Method: Participants w... Read More about Psychosocial stress and brain function in adolescent psychopathology.