Outputs (3)

Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism (2024)
Journal Article
Shur, N. F., Simpson, E. J., Crossland, H., Constantin, D., Cordon, S. M., Constantin-Teodosiu, D., Stephens, F. B., Brook, M. S., Atherton, P. J., Smith, K., Wilkinson, D. J., Mougin, O. E., Bradley, C., Macdonald, I. A., & Greenhaff, P. L. (2024). Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism. Journal of Cachexia, Sarcopenia and Muscle, 15(2), 603-614. https://doi.org/10.1002/jcsm.13431

Background
Bed-rest (BR) of only a few days duration reduces muscle protein synthesis and induces skeletal muscle atrophy and insulin resistance, but the scale and juxtaposition of these events have not been investigated concurrently in the same ind... Read More about Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism.

Liver glycogen stores via 13C magnetic resonance spectroscopy in healthy children: randomized, controlled study (2023)
Journal Article
Horstman, A. M., Bawden, S. J., Spicer, A., Darwish, N., Goyer, A., Egli, L., Rupp, N., Minehira, K., Gowland, P., Breuillé, D., Macdonald, I. A., & Simpson, E. J. (2023). Liver glycogen stores via 13C magnetic resonance spectroscopy in healthy children: randomized, controlled study. American Journal of Clinical Nutrition, 117(4), 709-716. https://doi.org/10.1016/j.ajcnut.2023.01.014

Background: Owing to its role in glucose homeostasis, liver glycogen concentration ([LGly]) can be a marker of altered metabolism seen in disorders that impact the health of children. However, there is a paucity of normative data for this measure in... Read More about Liver glycogen stores via 13C magnetic resonance spectroscopy in healthy children: randomized, controlled study.

Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease (2018)
Journal Article
Sargeant, J. A., Bawden, S., Aithal, G. P., Simpson, E. J., Macdonald, I. A., Turner, M. C., Cegielski, J., Smith, K., Dorling, J. L., Gowland, P. A., Nimmo, M. A., & King, J. A. (2018). Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease. European Journal of Applied Physiology, 118(4), 817-828. https://doi.org/10.1007/s00421-018-3818-y

Purpose: This study examined the feasibility of sprint interval exercise training (SIT) for men with non-alcoholic fatty liver disease (NAFLD) and its effects on intrahepatic triglyceride (IHTG), insulin sensitivity (hepatic and peripheral), visceral... Read More about Effects of sprint interval training on ectopic lipids and tissue-specific insulin sensitivity in men with non-alcoholic fatty liver disease.