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Source reconstruction without an MRI using optically pumped magnetometer based magnetoencephalography (2025)
Journal Article
Rhodes, N., Rier, L., Boto, E., Hill, R., & Brookes, M. J. (2025). Source reconstruction without an MRI using optically pumped magnetometer based magnetoencephalography. Imaging Neuroscience, 3, Article IMAG.a.8. https://doi.org/10.1162/imag.a.8

Source modelling in magnetoencephalography (MEG) infers the spatial origins of electrophysiological signals in the brain. Typically, this requires an anatomical MRI scan of the subject’s head, from which models of the magnetic fields generated by the... Read More about Source reconstruction without an MRI using optically pumped magnetometer based magnetoencephalography.

Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial (2025)
Journal Article
Acherman, Y. I. Z., Arebi, N., Arthurs, E., Bemelman, W. A., van der Bilt, J. D. W., Braat, H., Brink, M. A., Brookes, M., Brown, J. P. Y., Brown, S. R., Buskens, C. J., Consten, E. C. J., Cooney, R., Crolla, R. M. P. H., Davies, R. J., Depla, A. C. T. M., D'Haens, G. R., Dijkgraaf, M. G. W., Doherty, G., van Duijvendijk, P., …van der Zanden, E. P. M. (2025). Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial. The Lancet Gastroenterology & Hepatology, 10(6), 550-561. https://doi.org/10.1016/S2468-1253%2825%2900026-3

Background
The appendix might have an immunomodulatory role in ulcerative colitis. Appendicectomy has been suggested as a potentially therapeutic intervention to maintain remission in ulcerative colitis. We aimed to evaluate the clinical effectivene... Read More about Appendicectomy plus standard medical therapy versus standard medical therapy alone for maintenance of remission in ulcerative colitis (ACCURE): a pragmatic, open-label, international, randomised trial.

Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury (2025)
Journal Article
Sassani, M., Ghafari, T., Arachchige, P. R. W., Idrees, I., Gao, Y., Waitt, A., Weaver, S. R. C., Mazaheri, A., Lyons, H. S., Grech, O., Thaller, M., Witton, C., Bagshaw, A. P., Wilson, M., Park, H., Brookes, M., Novak, J., Mollan, S. P., Hill, L. J., Lucas, S. J. E., …Fernández-Espejo, D. (2025). Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury. Brain Communications, 7(2), Article fcaf120. https://doi.org/10.1093/braincomms/fcaf120

There is unmet clinical need for biomarkers to predict recovery or the development of long-term sequelae of mild traumatic brain injury, a highly prevalent condition causing a constellation of disabling symptoms. A substantial proportion of patients... Read More about Current and prospective roles of magnetic resonance imaging in mild traumatic brain injury.

Wearable magnetoencephalography in a lightly shielded environment (2024)
Journal Article
Holmes, N., Leggett, J., Hill, R. M., Rier, L., Boto, E., Schofield, H., Hayward, T., Dawson, E., Woolger, D., Shah, V., Taulu, S., Brookes, M. J., & Bowtell, R. (2025). Wearable magnetoencephalography in a lightly shielded environment. IEEE Transactions on Biomedical Engineering, 72(2), 609-618. https://doi.org/10.1109/tbme.2024.3465654

Wearable magnetoencephalography based on optically pumped magnetometers (OPM-MEG) offers non-invasive and high-fidelity measurement of human brain electrophysiology. The flexibility of OPM-MEG also means it can be deployed in participants of all ages... Read More about Wearable magnetoencephalography in a lightly shielded environment.

Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D. O., Boto, E., Holmes, N., Hill, R. M., Reina Rivero, G., Shah, V., Doyle, C., Osborne, J., Bowtell, R. W., Taylor, M., & Brookes, M. J. (2024). Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography. eLife, 13, Article RP94561. https://doi.org/10.7554/elife.94561.3

Neural oscillations mediate the coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only an important neuroscientific question but could also shed lig... Read More about Tracking the neurodevelopmental trajectory of beta band oscillations with optically pumped magnetometer-based magnetoencephalography.

Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG (2024)
Journal Article
Seedat, Z. A., Pier, K. S., Holmes, N., Rea, M., Al-Hilaly, L., Tierney, T. M., Embury, C. M., Pardington, R., Mullinger, K. J., Cross, J. H., Boto, E., & Brookes, M. J. (2024). Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG. Imaging Neuroscience, 2, 1-15. https://doi.org/10.1162/imag_a_00179

Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively measure human brain electrophysiology. They differ in nature; MEG offers better performance whilst EEG (a wearable platform) is more practical. They are also complementary,... Read More about Simultaneous whole-head electrophysiological recordings using EEG and OPM-MEG.

Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics (2024)
Journal Article
Coleman, S. C., Seedat, Z. A., Pakenham, D. O., Quinn, A. J., Brookes, M. J., Woolrich, M. W., & Mullinger, K. J. (2024). Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics. Human Brain Mapping, 45(7), Article e26700. https://doi.org/10.1002/hbm.26700

The post-movement beta rebound has been studied extensively using magnetoencephalography (MEG) and is reliably modulated by various task parameters as well as illness. Our recent study showed that rebounds, which we generalise as “post-task responses... Read More about Post‐task responses following working memory and movement are driven by transient spectral bursts with similar characteristics.

The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study (2024)
Journal Article
Rier, L., Rhodes, N., Pakenham, D., Boto, E., Holmes, N., Hill, R. M., Rivero, G. R., Shah, V., Doyle, C., Osborne, J., Bowtell, R., Taylor, M. J., & Brookes, M. J. (2024). The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study. eLife, Article 94561v1. https://doi.org/10.7554/eLife.94561.1

Neural oscillations mediate coordination of activity within and between brain networks, supporting cognition and behaviour. How these processes develop throughout childhood is not only a critical neuroscientific question but could also shed light on... Read More about The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study.

Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping (2023)
Journal Article
Hobson, P. J., Hardwicke, N. L., Davis, A., Smith, T. X., Morley, C., Packer, M., Holmes, N., Weil, M. A., Brookes, M. J., Bowtell, R., & Fromhold, M. (2023). Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping. IEEE Transactions on Instrumentation and Measurement, 72, Article 1005815. https://doi.org/10.1109/TIM.2023.3284138

Adaptable, low-cost, coils designed by carefully selecting the arrangements and geometries of simple primitive units are used to generate magnetic fields for diverse applications. These extend from magnetic resonance and fundamental physics experimen... Read More about Designing Optimal Loop, Saddle, and Ellipse-Based Magnetic Coils by Spherical Harmonic Mapping.