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Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study (2022)
Journal Article
Seedat, Z. A., Rier, L., Gascoyne, L. E., Cook, H., Woolrich, M. W., Quinn, A. J., Roberts, T. P. L., Furlong, P. L., Armstrong, C., St. Pier, K., Mullinger, K. J., Marsh, E. D., Brookes, M. J., & Gaetz, W. (2022). Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study. Human Brain Mapping, https://doi.org/10.1002/hbm.26118

Epilepsy is a highly heterogeneous neurological disorder with variable etiology, manifestation, and response to treatment. It is imperative that new models of epileptiform brain activity account for this variability, to identify individual needs and... Read More about Mapping Interictal activity in epilepsy using a hidden Markov model: A magnetoencephalography study.

Turning OPM-MEG into a Wearable Technology (2022)
Book Chapter
Rhodes, N., Holmes, N., Hill, R., Barnes, G., Bowtell, R., Brookes, M., & Boto, E. (2022). Turning OPM-MEG into a Wearable Technology. In E. Labyt, T. Sander, & R. Wakai (Eds.), Flexible High Performance Magnetic Field Sensors: On-Scalp Magnetoencephalography and Other Applications (195-223). Springer International Publishing. https://doi.org/10.1007/978-3-031-05363-4_11

This chapter explores the use of optically pumped magnetometers (OPMs) as a tool for magnetoencephalography (MEG). Conventional MEG systems use superconducting quantum interference devices (SQUIDs) to measure the femto-Tesla-level magnetic fields at... Read More about Turning OPM-MEG into a Wearable Technology.

A lightweight magnetically shielded room with active shielding (2022)
Journal Article
Holmes, N., Rea, M., Chalmers, J., Leggett, J., Edwards, L. J., Nell, P., Pink, S., Patel, P., Wood, J., Murby, N., Woolger, D., Dawson, E., Mariani, C., Tierney, T. M., Mellor, S., O’Neill, G. C., Boto, E., Hill, R. M., Shah, V., Osborne, J., …Bowtell, R. (2022). A lightweight magnetically shielded room with active shielding. Scientific Reports, 12, Article 13561. https://doi.org/10.1038/s41598-022-17346-1

Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision magnetic field measurements such as magnetoencephalography (MEG). Optically pump... Read More about A lightweight magnetically shielded room with active shielding.

Predicting time-resolved electrophysiological brain networks from structural eigenmodes (2022)
Journal Article
Tewarie, P., Prasse, B., Meier, J., Mandke, K., Warrington, S., Stam, C. J., Brookes, M. J., Van Mieghem, P., Sotiropoulos, S. N., & Hillebrand, A. (2022). Predicting time-resolved electrophysiological brain networks from structural eigenmodes. Human Brain Mapping, https://doi.org/10.1002/hbm.25967

How temporal modulations in functional interactions are shaped by the underlying anatomical connections remains an open question. Here, we analyse the role of structural eigenmodes, in the formation and dissolution of temporally evolving functional b... Read More about Predicting time-resolved electrophysiological brain networks from structural eigenmodes.

On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children (2022)
Journal Article
Feys, O., Corvilain, P., Aeby, A., Sculier, C., Holmes, N., Brookes, M., Goldman, S., Wens, V., & De Tiège, X. (2022). On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children. Radiology, 304(2), 429-434. https://doi.org/10.1148/radiol.212453

Background Magnetoencephalography (MEG) is an established method used to detect and localize focal interictal epileptiform discharges (IEDs). Current MEG systems house hundreds of cryogenic sensors in a rigid, one-size-fits-all helmet, which results... Read More about On-Scalp Optically Pumped Magnetometers versus Cryogenic Magnetoencephalography for Diagnostic Evaluation of Epilepsy in School-aged Children.

Using OPM-MEG in contrasting magnetic environments (2022)
Journal Article
Hill, R. M., Devasagayam, J., Holmes, N., Boto, E., Shah, V., Osborne, J., Safar, K., Worcester, F., Mariani, C., Dawson, E., Woolger, D., Bowtell, R., Taylor, M. J., & Brookes, M. J. (2022). Using OPM-MEG in contrasting magnetic environments. NeuroImage, 253, Article 119084. https://doi.org/10.1016/j.neuroimage.2022.119084

Magnetoencephalography (MEG) has been revolutionised by optically pumped magnetometers (OPMs). “OPM-MEG” offers higher sensitivity, better spatial resolution, and lower cost than conventional instrumentation based on superconducting quantum interfere... Read More about Using OPM-MEG in contrasting magnetic environments.

Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm (2022)
Journal Article
Packer, M., Hobson, P. J., Davis, A., Holmes, N., Leggett, J., Glover, P., Hardwicke, N. L., Brookes, M. J., Bowtell, R., & Fromhold, T. M. (2022). Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm. Journal of Applied Physics, 131(9), Article 093902. https://doi.org/10.1063/5.0071986

Magnetically sensitive experiments and newly developed quantum technologies with integrated high-permeability magnetic shields require increasing control of their magnetic field environment and reductions in size, weight, power, and cost. However, ma... Read More about Magnetic field design in a cylindrical high-permeability shield: The combination of simple building blocks and a genetic algorithm.

Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children (2022)
Journal Article
Boto, E., Shah, V., Hill, R. M., Rhodes, N., Osborne, J., Doyle, C., Holmes, N., Rea, M., Leggett, J., Bowtell, R., & Brookes, M. J. (2022). Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children. NeuroImage, 252, Article 119027. https://doi.org/10.1016/j.neuroimage.2022.119027

Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility to accommodate any head size, uniform coverage, free movement duri... Read More about Triaxial detection of the neuromagnetic field using optically-pumped magnetometry: feasibility and application in children.

The oscillatory effects of rhythmic median nerve stimulation (2022)
Journal Article
Houlgreave, M. S., Morera Maiquez, B., Brookes, M. J., & Jackson, S. R. (2022). The oscillatory effects of rhythmic median nerve stimulation. NeuroImage, 251, Article 118990. https://doi.org/10.1016/j.neuroimage.2022.118990

Entrainment of brain oscillations can be achieved using rhythmic non-invasive brain stimulation, and stimulation of the motor cortex at a frequency associated with sensorimotor inhibition can impair motor responses. Despite the potential for therapeu... Read More about The oscillatory effects of rhythmic median nerve stimulation.