Skip to main content

Research Repository

Advanced Search

Outputs (159)

A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis (2016)
Journal Article
Refahi, Y., Brunoud, G., Farcot, E., Jean-Marie, A., Pulkkinen, M., Vernoux, T., & Godin, C. (2016). A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis. eLife, 5, Article e14093. https://doi.org/10.7554/eLife.14093

Exploration of developmental mechanisms classically relies on analysis of pattern regularities. Whether disorders induced by biological noise may carry information on building principles of developmental systems is an important debated question. Here... Read More about A stochastic multicellular model identifies biological watermarks from disorders in self-organized patterns of phyllotaxis.

Nonparametric Statistical Methods on Manifolds (2016)
Book Chapter
Dryden, I. L., Le, H., Preston, S. P., & Wood, A. T. A. (2016). Nonparametric Statistical Methods on Manifolds. In M. Denker, & E. C. Waymire (Eds.), Rabi N. Bhattacharya: Selected Papers (587-597). Springer. https://doi.org/10.1007/978-3-319-30190-7_17

One of the many fundamental contributions that Rabi Bhattacharya, together with his coauthors, has made is the development of a general nonparametric theory of statistical inference on manifolds, in particular related to both intrinsic and extrinsic... Read More about Nonparametric Statistical Methods on Manifolds.

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth (2016)
Journal Article
Brown, D. M., Williams, H., Ryan, K., Wilson, T., Daniel, Z. C., Mareko, M. H. D., Emes, R. D., Harris, D. W., Wattis, J. A., Dryden, I. L., Hodgman, T. C., Brameld, J. M., & Parr, T. (2016). Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth. Scientific Reports, 6(1), https://doi.org/10.1038/srep28693

We aimed to identify novel molecular mechanisms for muscle growth during administration of anabolic agents. Growing pigs (Duroc/(Landrace/Large-White)) were administered Ractopamine (a beta-adrenergic agonist; BA; 20ppm in feed) or Reporcin (recombin... Read More about Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth.

Computational modelling of multiscale, multiphase fluid mixtures with application to tumour growth (2016)
Journal Article
Collis, J., Hubbard, M. E., & O'Dea, R. D. (2016). Computational modelling of multiscale, multiphase fluid mixtures with application to tumour growth. Computer Methods in Applied Mechanics and Engineering, 309, https://doi.org/10.1016/j.cma.2016.06.015

In this work we consider the discretization of a recently formulated (Collis et al., [22]) multiscale model for drug- and nutrient-limited tumour growth. The key contribution of this work is the proposal of a discontinuous Galerkin finite element sch... Read More about Computational modelling of multiscale, multiphase fluid mixtures with application to tumour growth.

Mathematical and Numerical Modelling of Wave Impact on Wave-Energy Buoys (2016)
Presentation / Conference Contribution
Kalogirou, A., & Bokhove, O. (2016, June). Mathematical and Numerical Modelling of Wave Impact on Wave-Energy Buoys. Presented at ASME 2016 35th International Conference on Ocean, Offshore and Arctic Engineering, Busan, South Korea

We report on the mathematical and numerical modelling of amplified rogue waves driving a wave-energy device in a contraction. This wave-energy device consists of a floating buoy attached to an AC-induction motor and constrained to move upward only in... Read More about Mathematical and Numerical Modelling of Wave Impact on Wave-Energy Buoys.

The effects of insulin resistance on individual tissues: an application of a mathematical model of metabolism in humans (2016)
Journal Article
Pearson, T., Wattis, J. A., King, J., McDonald, I., & Mazzatti, D. (in press). The effects of insulin resistance on individual tissues: an application of a mathematical model of metabolism in humans. Bulletin of Mathematical Biology, 78(6), https://doi.org/10.1007/s11538-016-0181-1

Whilst the human body expends energy constantly, the human diet consists of a mix of carbohydrates and fats delivered in a discontinuous manner. To deal with this sporadic supply of energy, there are transport, storage and utilisation mechanisms, for... Read More about The effects of insulin resistance on individual tissues: an application of a mathematical model of metabolism in humans.

An optimally efficient technique for the solution of systems of nonlinear parabolic partial differential equations (2016)
Journal Article
Yang, F.-W., Goodyer, C. E., Hubbard, M. E., & Jimack, P. K. (2017). An optimally efficient technique for the solution of systems of nonlinear parabolic partial differential equations. Advances in Engineering Software, 103, https://doi.org/10.1016/j.advengsoft.2016.06.003

This paper describes a new software tool that has been developed for the efficient solution of systems of linear and nonlinear partial differential equations (PDEs) of parabolic type. Specifically, the software is designed to provide optimal computat... Read More about An optimally efficient technique for the solution of systems of nonlinear parabolic partial differential equations.

Markov decision process algorithms for wealth allocation problems with defaultable bonds (2016)
Journal Article
Pérez López, I., Hodge, D., & Le, H. (in press). Markov decision process algorithms for wealth allocation problems with defaultable bonds. Advances in Applied Probability, 48(2), https://doi.org/10.1017/apr.2016.6

This paper is concerned with analysing optimal wealth allocation techniques within a defaultable financial market similar to Bielecki and Jang (2007). It studies a portfolio optimization problem combining a continuous-time jump market and a defaultab... Read More about Markov decision process algorithms for wealth allocation problems with defaultable bonds.

Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century (2016)
Journal Article
Hill, A. P., Perry, M. D., Abi-Gerges, N., Couderc, J.-P., Fermini, B., Hancox, J. C., Knollmann, B. C., Mirams, G. R., Skinner, J., Zareba, W., & Vandenberg, J. I. (2016). Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century. Journal of Physiology, 594(23), 6893-6908. https://doi.org/10.1113/jp272015