Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes
(2016)
Journal Article
Lee, D. S., Durán-Peña, M. J., Burroughs, L., & Woodward, S. (in press). Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes. Chemistry - A European Journal, 2016(22), https://doi.org/10.1002/chem.201600607
The reaction of excess TMSCl and LiCCl2Br at low temperature is a technically simple high yield route to TMSCCl2Br. The latter is a stable source of the dichlorobromomethide carbanion, which undergoes 1,4-addition with cyclic nitroalkenes and (E)-fum... Read More about Efficient preparation of TMSCCl2Br and its use in dichlorocyclopropanation of electron deficient alkenes.