Outputs (165)

Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols (2017)
Journal Article
Alsafadi, D., Alsalman, S., & Paradisi, F. (in press). Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols. Organic and Biomolecular Chemistry, https://doi.org/10.1039/C7OB02299A

Enzymatic synthesis of enantiopure aromatic secondary alcohols (including substituted, heteroaromatic and bicyclic structures) were carried out using the halophilic alcohol dehydrogenase ADH2 from Haloferax volcanii (HvADH2). This enzyme showed an un... Read More about Extreme halophilic alcohol dehydrogenase mediated highly efficient syntheses of enantiopure aromatic alcohols.

The contrasting effects of diethylmethylamine during reduction of protons and oxidation of formic acid in diethylmethylammonium-based protic ionic liquids (2017)
Journal Article
Goodwin, S., Muhammad, S., Tuan, L.-P., & Walsh, D. (2018). The contrasting effects of diethylmethylamine during reduction of protons and oxidation of formic acid in diethylmethylammonium-based protic ionic liquids. Journal of Electroanalytical Chemistry, 819, https://doi.org/10.1016/j.jelechem.2017.10.021

Ionic liquids are formally defined as liquids that consist entirely of ions, and which are liquid below 100 C. As these liquids are being proposed for use in a range of electrochemical devices and applications, understanding the electrochemical beha... Read More about The contrasting effects of diethylmethylamine during reduction of protons and oxidation of formic acid in diethylmethylammonium-based protic ionic liquids.

A New, Practical One-Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides (2017)
Journal Article
Izzo, F., Schäfer, M., Stockman, R., & Lücking, U. (2017). A New, Practical One-Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides. Chemistry - A European Journal, 23(60), 15189-15193. https://doi.org/10.1002/chem.201703272

Unprotected tertiary sulfonimidamides have been prepared in good to excellent yields in a one‐pot transformation from tertiary sulfinamides through NH transfer. The reaction is mediated by commercially available (diacetoxyiodo)benzene and ammonium ca... Read More about A New, Practical One-Pot Synthesis of Unprotected Sulfonimidamides by Transfer of Electrophilic NH to Sulfinamides.

Development of a series of bis-triazoles as G-quadruplex ligands (2017)
Journal Article
Saleh, M., Laughton, C. A., Bradshaw, T. D., & Moody, C. J. (in press). Development of a series of bis-triazoles as G-quadruplex ligands. RSC Advances, 7, https://doi.org/10.1039/c7ra07257k

Maintenance of telomeres – specialized complexes that protect the ends of chromosomes – is provided by the enzyme complex telomerase, which is a key factor that is activated in more than 80% of cancer cells, but absent in most normal cells. Targeting... Read More about Development of a series of bis-triazoles as G-quadruplex ligands.

The alteration of intra-ligand donor-acceptor interactions through torsional connectivity in substituted Re-dppz complexes (2017)
Journal Article
Adams, B., Shillito, G. E., Salm, H. V. D., Horvath, R., Larsen, C. B., Sun, . X.-Z., …Gordon, K. C. (2017). The alteration of intra-ligand donor-acceptor interactions through torsional connectivity in substituted Re-dppz complexes. Inorganic Chemistry, 56(21), 12967-12977. https://doi.org/10.1021/acs.inorgchem.7b01710

The ground and excited properties of a series of [ReCl(CO)3(dppz)] complexes with substituted donor groups have been investigated. Alteration of donor-acceptor communication through modulation of torsional angle and the number and nature of the donor... Read More about The alteration of intra-ligand donor-acceptor interactions through torsional connectivity in substituted Re-dppz complexes.

Connections between variation principles at the interface of wave-function and density-functional theories (2017)
Journal Article
Irons, T. J., Furness, J. W., Ryley, M. S., Zemen, J., Helgaker, T., & Teale, A. M. (2017). Connections between variation principles at the interface of wave-function and density-functional theories. Journal of Chemical Physics, 147(13), Article 134107. https://doi.org/10.1063/1.4985883

A recently proposed variation principle [N. I. Gidopoulos, Phys. Rev. A 83, 040502(R) (2011)] for the determination of Kohn–Sham effective potentials is examined and ex- tended to arbitrary electron-interaction strengths and to mixed states. Comparis... Read More about Connections between variation principles at the interface of wave-function and density-functional theories.

Tuneable 3D printed bioreactors for transaminations under continuous-flow (2017)
Journal Article
Peris, E., Okafor, O., Kulchinskaja, E., Goodridge, R. D., Luis, S. V., Garcia-Verdugo, E., …Sans, V. (2017). Tuneable 3D printed bioreactors for transaminations under continuous-flow. Green Chemistry, 19(22), https://doi.org/10.1039/C7GC02421E

A method to efficiently immobilize enzymes on 3D printed continuous-flow devices is presented. Application of these chemically modified devices enables rapid screening of immobilization mechanisms and reaction conditions, simple transfer of optimised... Read More about Tuneable 3D printed bioreactors for transaminations under continuous-flow.

Total synthesis of (−)-aritasone via the ultra-high pressure hetero-Diels–Alder dimerisation of (−)-pinocarvone (2017)
Journal Article
Uroos, M., Pitt, P., Harwood, L., Lewis, W., Blake, A. J., & Hayes, C. J. (in press). Total synthesis of (−)-aritasone via the ultra-high pressure hetero-Diels–Alder dimerisation of (−)-pinocarvone. Organic and Biomolecular Chemistry, 15(40), https://doi.org/10.1039/C7OB02204B

This paper describes a total synthesis of the terpene-derived natural product aritasone via the hetero-Diels-Alder [4+2] cyclodimerisation of pinocarvove, which represents the proposed biosyntheic route. The hetero-Diels-Alder dimerisation of pinoca... Read More about Total synthesis of (−)-aritasone via the ultra-high pressure hetero-Diels–Alder dimerisation of (−)-pinocarvone.

Halogen-substituted ureas for anion binding: solid state and solution studies (2017)
Journal Article
Casula, A., Fornasier, M., Montis, R., Bettoschi, A., Argent, S. P., Blake, A. J., …Caltagirone, C. (in press). Halogen-substituted ureas for anion binding: solid state and solution studies. Supramolecular Chemistry, https://doi.org/10.1080/10610278.2017.1377343

Herein, we report the synthesis and the anion binding properties of a family of N,N′-diphenylureas L1-L15, bearing on the aromatic ring(s) halogens (chlorine and iodine) and/or nitro or trifluoromethyl electron-withdrawing groups. The analysis of the... Read More about Halogen-substituted ureas for anion binding: solid state and solution studies.

Comparison of alkene hydrogenation in carbon nanoreactors of different diameters: probing the effects of nanoscale confinement on ruthenium nanoparticle catalysis (2017)
Journal Article
Aygun, M., Stoppiello, C. T., Lebedeva, M. A., Smith, E. F., Gimenez-Lopez, M. D. C., Khlobystov, A. N., & Chamberlain, T. W. (in press). Comparison of alkene hydrogenation in carbon nanoreactors of different diameters: probing the effects of nanoscale confinement on ruthenium nanoparticle catalysis. Journal of Materials Chemistry A, 40(5), https://doi.org/10.1039/C7TA03691D

The catalytic properties of ruthenium nanoparticles (RuNPs) supported in carbon nanoreactors of different diameters – single walled carbon nanotubes (SWNTs, width of cavity 1.5 nm) and hollow graphitised nanofibers (GNFs, width of cavity 50-70 nm) –... Read More about Comparison of alkene hydrogenation in carbon nanoreactors of different diameters: probing the effects of nanoscale confinement on ruthenium nanoparticle catalysis.