Outputs (10)

Green enzymatic synthesis and processing of poly (cis-9,10-epoxy-18-hydroxyoctadecanoic acid) in supercritical carbon dioxide (scCO2) (2021)
Journal Article
Sagnelli, D., Vestri, A., Curia, S., Taresco, V., Santagata, G., Johansson, M. K., & Howdle, S. M. (2021). Green enzymatic synthesis and processing of poly (cis-9,10-epoxy-18-hydroxyoctadecanoic acid) in supercritical carbon dioxide (scCO2). European Polymer Journal, 161, Article 110827. https://doi.org/10.1016/j.eurpolymj.2021.110827

There is significant potential for industrial use of renewables for a wide range of materials demanded by society. Plants, trees and algae are increasingly attracting attention as sustainable sources for functionalised and polymerizable building bloc... Read More about Green enzymatic synthesis and processing of poly (cis-9,10-epoxy-18-hydroxyoctadecanoic acid) in supercritical carbon dioxide (scCO2).

Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods (2021)
Journal Article
Cuzzucoli Crucitti, V., Contreas, L., Taresco, V., Howard, S. C., Dundas, A. A., Limo, M. J., Nisisako, T., Williams, P. M., Williams, P., Alexander, M. R., Wildman, R. D., Muir, B. W., & Irvine, D. J. (2021). Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods. ACS Applied Materials and Interfaces, 13(36), 43290-43300. https://doi.org/10.1021/acsami.1c08662

We report the first successful combination of three distinct high-throughput techniques to deliver the accelerated design, synthesis, and property screening of a library of novel, bio-instructive, polymeric, comb-graft surfactants. These three-dimens... Read More about Generation and Characterization of a Library of Novel Biologically Active Functional Surfactants (Surfmers) Using Combined High-Throughput Methods.

Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers (2021)
Journal Article
Ruiz-Cantu, L., Trindade, G. F., Taresco, V., Zhou, Z., He, Y., Burroughs, L., Clark, E. A., Rose, F. R., Tuck, C., Hague, R., Roberts, C. J., Alexander, M., Irvine, D. J., & Wildman, R. D. (2021). Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers. ACS Applied Materials and Interfaces, 13(33), 38969-38978. https://doi.org/10.1021/acsami.1c07850

Controlling the microstructure of materials by means of phase separation is a versatile tool for optimizing material properties. Phase separation has been exploited to fabricate intricate microstructures in many fields including cell biology, tissue... Read More about Bespoke 3D-Printed Polydrug Implants Created via Microstructural Control of Oligomers.

Silver- and Zinc-Decorated Polyurethane Ionomers with Tunable Hard/Soft Phase Segregation (2021)
Journal Article
Rapone, I., Taresco, V., Lisio, V. D., Piozzi, A., & Francolini, I. (2021). Silver- and Zinc-Decorated Polyurethane Ionomers with Tunable Hard/Soft Phase Segregation. International Journal of Molecular Sciences, 22(11), 1-16. https://doi.org/10.3390/ijms22116134

Segmented polyurethane ionomers find prominent applications in the biomedical field since they can combine the good mechanical and biostability properties of polyurethanes (PUs) with the strong hydrophilicity features of ionomers. In this work, PU io... Read More about Silver- and Zinc-Decorated Polyurethane Ionomers with Tunable Hard/Soft Phase Segregation.

Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects (2021)
Journal Article
Jacob, P. L., Ruiz Cantu, L. A., Pearce, A. K., He, Y., Lentz, J. C., Moore, J. C., Machado, F., Rivers, G., Apebende, E., Fernandez, M. R., Francolini, I., Wildman, R., Howdle, S. M., & Taresco, V. (2021). Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects. Polymer, 228, Article 123912. https://doi.org/10.1016/j.polymer.2021.123912

Enzymatically synthesised poly(glycerol adipate) (PGA) has shown a palette of key desirable properties required for a biomaterial to be considered a ‘versatile polymeric tool’ in the field of drug delivery. PGA and its variations can self-assemble in... Read More about Poly (glycerol adipate) (PGA) backbone modifications with a library of functional diols: Chemical and physical effects.

Functionalisable Epoxy-rich Electrospun Fibres Based on Renewable Terpene for Multi-Purpose Applications (2021)
Journal Article
Montanari, U., Cocchi, D., Brugo, T. M., Pollicino, A., Taresco, V., Romero Fernandez, M., Moore, J. C., Sagnelli, D., Paradisi, F., Zucchelli, A., Howdle, S. M., & Gualandi, C. (2021). Functionalisable Epoxy-rich Electrospun Fibres Based on Renewable Terpene for Multi-Purpose Applications. Polymers, 13(11), Article 1804. https://doi.org/10.3390/polym13111804

New bio-based polymers capable of either outperforming fossil-based alternatives or possessing new properties and functionalities are of relevant interest in the framework of the circular economy. In this work, a novel bio-based polycarvone acrylate... Read More about Functionalisable Epoxy-rich Electrospun Fibres Based on Renewable Terpene for Multi-Purpose Applications.

RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers (2021)
Journal Article
Atkinson, R. L., Monaghan, O., Elsmore, M. T., Topham, P. D., Toolan, D. T. W., Derry, M. J., Taresco, V., Stockman, R., De Focatiis, D. S., Irvine, D. J., & Howdle, S. M. (2021). RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers. Polymer Chemistry, 12(21), 3177-3189. https://doi.org/10.1039/d1py00326g

Terpenes are ideal candidates for sustainable polymer feedstocks, due to their natural abundance and availability from existing waste streams. Previously, we have shown that a range of terpene(meth)acrylate monomers can be synthesised from the most c... Read More about RAFT polymerisation of renewable terpene (meth)acrylates and the convergent synthesis of methacrylate-acrylate-methacrylate triblock copolymers.

Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media (2021)
Journal Article
Goddard, A. R., Apebende, E. A., Lentz, J. C., Carmichael, K., Taresco, V., Irvine, D. J., & Howdle, S. M. (2021). Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media. Polymer Chemistry, 12(20), 2992-3003. https://doi.org/10.1039/d1py00415h

Sustainable and biobased surfactants are required for a wide range of everyday applications. Key drivers are cost, activity and efficiency of production. Polycondensation is an excellent route to build surfactant chains from bio-sourced monomers, but... Read More about Synthesis of water-soluble surfactants using catalysed condensation polymerisation in green reaction media.

Porous hollow TiO2 microparticles for photocatalysis: exploiting novel ABC triblock terpolymer templates synthesised in supercritical CO2 (2021)
Journal Article
Larder, R. R., Bennett, T. M., Blankenship, L. S., Alves Fernandes, J., Husband, B. K., Atkinson, R. L., Derry, M. J., Thomas William Toolan, D., Centurion, H. A., Topham, P. D., Vitalino Goncalves, R., Taresco, V., & Howdle, S. M. (2021). Porous hollow TiO2 microparticles for photocatalysis: exploiting novel ABC triblock terpolymer templates synthesised in supercritical CO2. Polymer Chemistry, 12(19), 2904-2913. https://doi.org/10.1039/d1py00334h

Reversible addition-fragmentation chain transfer (RAFT) mediated dispersion polymerisation in supercritical carbon dioxide (scCO2) is an efficient and green method for synthesising block copolymer microparticles with internal nanostructures. Here we... Read More about Porous hollow TiO2 microparticles for photocatalysis: exploiting novel ABC triblock terpolymer templates synthesised in supercritical CO2.

The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core (2021)
Journal Article
Jenkins, T., Northall, S. J., Ptchelkine, D., Lever, R., Cubbon, A., Betts, H., Taresco, V., Cooper, C. D. O., McHugh, P. J., Soultanas, P., & Bolt, E. L. (2021). The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core. NAR Cancer, 3(1), Article zcaa043. https://doi.org/10.1093/narcan/zcaa043

Genome instability is a characteristic enabling factor for carcinogenesis. HelQ helicase is a component of human DNA maintenance systems that prevent or reverse genome instability arising during DNA replication. Here, we provide details of the molecu... Read More about The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core.