Outputs (52)

Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent (2024)
Journal Article
Mehner, F., Hopkins, B., Reynolds-Green, M., Keddie, D. J., Howdle, S. M., & Gaitzsch, J. (2024). Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent. Polymer, 309, Article 127373. https://doi.org/10.1016/j.polymer.2024.127373

Radical ring opening polymerisation (RROP) of cyclic ketene acetals (CKAs) is an attractive technique to synthesize branched, (bio)degradable polyesters. However, CKAs as monomers of RROP suffer from hydrolysis lability, making aqueous heterogeneous... Read More about Supercritical RROP: Exploring the radical ring-opening polymerisation of 2-methylene-1,3,6-trioxocane in supercritical CO2 as a green solvent.

A facile one step route that introduces functionality to polymer powders for laser sintering (2024)
Journal Article
Krumins, E., Crawford, L. A., Rogers, D. M., Machado, F., Taresco, V., East, M., …Howdle, S. M. (2024). A facile one step route that introduces functionality to polymer powders for laser sintering. Nature Communications, 15(1), Article 3137. https://doi.org/10.1038/s41467-024-47376-4

Laser Sintering (LS) is a type of Additive Manufacturing (AM) exploiting laser processing of polymeric particles to produce 3D objects. Because of its ease of processability and thermo-physical properties, polyamide-12 (PA-12) represents ~95% of the... Read More about A facile one step route that introduces functionality to polymer powders for laser sintering.

Glycerol- and diglycerol-based polyesters: Evaluation of backbone alterations upon nano-formulation performance (2024)
Journal Article
Axioti, E., Dixon, E. G., Reynolds-Green, M., Alexander, E. C., Brugnoli, B., Keddie, D. J., …Taresco, V. (2024). Glycerol- and diglycerol-based polyesters: Evaluation of backbone alterations upon nano-formulation performance. Colloids and Surfaces B: Biointerfaces, 236, Article 113828. https://doi.org/10.1016/j.colsurfb.2024.113828

Despite the success of polyethylene glycol-based (PEGylated) polyesters in the drug delivery and biomedical fields, concerns have arisen regarding PEG's immunogenicity and limited biodegradability. In addition, inherent limitations, including limited... Read More about Glycerol- and diglycerol-based polyesters: Evaluation of backbone alterations upon nano-formulation performance.

Glycerol-based sustainably sourced resin for volumetric printing (2024)
Journal Article
Krumins, E., Lentz, J. C., Sutcliffe, B., Sohaib, A., Jacob, P. L., Brugnoli, B., …Taresco, V. (2024). Glycerol-based sustainably sourced resin for volumetric printing. Green Chemistry, 26(3), 1345-1355. https://doi.org/10.1039/d3gc03607c

Volumetric Additive Manufacturing (VAM) represents a revolutionary advancement in the field of Additive Manufacturing, as it allows for the creation of objects in a single, cohesive process, rather than in a layer-by-layer approach. This innovative t... Read More about Glycerol-based sustainably sourced resin for volumetric printing.

Synthesis of core-shell polymer particles in supercritical carbon dioxide via iterative monomer addition (2023)
Journal Article
Kortsen, K., Reynolds-Green, M., Hopkins, B., McLellan, A., Derry, M. J., Topham, P. D., …Howdle, S. M. (2023). Synthesis of core-shell polymer particles in supercritical carbon dioxide via iterative monomer addition. Chemical Communications, 59(98), 14536-14539. https://doi.org/10.1039/d3cc04969h

A new, robust methodology for the synthesis of polystyrene-poly(methyl methacrylate) (PS-PMMA) core-shell particles using seeded dispersion polymerisation in supercritical carbon dioxide is reported, where the core-shell ratio can be controlled predi... Read More about Synthesis of core-shell polymer particles in supercritical carbon dioxide via iterative monomer addition.

Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells (2023)
Journal Article
Brugnoli, B., Mariano, A., Simonis, B., Bombelli, C., Sennato, S., Piozzi, A., …Francolini, I. (2023). Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells. Carbohydrate Polymer Technologies and Applications, 6, Article 100373. https://doi.org/10.1016/j.carpta.2023.100373

Polymers are among the most studied materials as drug carriers, due to their tunable chemical structure and ability to self-assemble to give different types of nanostructures. In this study, chitosan (CS) nanoparticles (NPs) were investigated as carr... Read More about Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B cells.

Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly (2023)
Journal Article
Phan, H., Cavanagh, R., Jacob, P., Destouches, D., Vacherot, F., Brugnoli, B., …Couturaud, B. (2023). Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly. Polymers, 15(14), Article 3070. https://doi.org/10.3390/polym15143070

Polymersomes are an exciting modality for drug delivery due to their structural similarity to biological cells and their ability to encapsulate both hydrophilic and hydrophobic drugs. In this regard, the current work aimed to develop multifunctional... Read More about Synthesis of Multifunctional Polymersomes Prepared by Polymerization-Induced Self-Assembly.

Modification of Linear Polyethylenimine with Supercritical CO2: From Fluorescent Materials to Covalent Cross-Links (2023)
Journal Article
Mees, M. A., McAllister, T. D., Curia, S., Howdle, S. M., & Hoogenboom, R. (2023). Modification of Linear Polyethylenimine with Supercritical CO2: From Fluorescent Materials to Covalent Cross-Links. Macromolecules, 56(7), 2841-2851. https://doi.org/10.1021/acs.macromol.2c02443

Along with their DNA binding ability, the secondary amines in linear polyethylenimine (L-PEI) units can also act as a reaction platform to introduce new functionalities. This renders the possibility to make a plethora of copolymers without the burden... Read More about Modification of Linear Polyethylenimine with Supercritical CO2: From Fluorescent Materials to Covalent Cross-Links.

Evaluation of two terpene-derived polymers as consolidants for archaeological wood (2023)
Journal Article
Cutajar, M., Braovac, S., Stockman, R. A., Howdle, S. M., & Harding, S. E. (2023). Evaluation of two terpene-derived polymers as consolidants for archaeological wood. Scientific Reports, 13(1), Article 3664. https://doi.org/10.1038/s41598-023-29785-5

The evaluation of two terpene-derived polymers, termed TPA6 and TPA7, as possible consolidants for archaeological wood was carried out. The overall objective of this work was to expand the non-aqueous treatment toolkit which is available for the cons... Read More about Evaluation of two terpene-derived polymers as consolidants for archaeological wood.

Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis (2023)
Journal Article
Fowler, H. R., O'Brien, D. M., Keddie, D. J., Alexander, C., Irvine, D. J., Stockman, R. A., …Taresco, V. (2023). Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis. Macromolecular Chemistry and Physics, 224(8), Article 2200446. https://doi.org/10.1002/macp.202200446

Polyols and polyacrylates have a wide range of applications in polymer synthesis as monomers, initiators, or building blocks in a variety of polymerization reaction types. With an ever-growing need to reduce the global dependency on fossil fuels, fin... Read More about Oxidation of Monoterpenes to Form Diols and Triols: A Versatile Toolbox for Polymer Synthesis.