Outputs (3)

Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach (2022)
Journal Article
O'Neill, E. C. (2023). Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach. FEMS Microbiology Letters, 370, Article fnac120. https://doi.org/10.1093/femsle/fnac120

Protein glycosylation, and in particular N-linked glycans, is a hallmark of eukaryotic cells and has been well-studied in mammalian cells and parasites. However, little research has been conducted to investigate the conservation and variation of prot... Read More about Glycosylated proteins in the protozoan alga Euglena gracilis: a proteomic approach.

Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world (2022)
Journal Article
Ebenezer, T. G. E., Low, R. S., O'Neill, E. C., Huang, I., DeSimone, A., Farrow, S. C., Field, R. A., Ginger, M. L., Guerrero, S. A., Hammond, M., Hampl, V., Horst, G., Ishikawa, T., Karnkowska, A., Linton, E. W., Myler, P., Nakazawa, M., Cardol, P., Sánchez-Thomas, R., Saville, B. J., …Field, M. C. (2022). Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world. Biology Open, 11(11), Article 059561. https://doi.org/10.1242/bio.059561

Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. Euglenoids combine a biotechnological potential with a unique position in the eukaryotic tree of life. In large part these micr... Read More about Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world.

Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis (2022)
Journal Article
Aldholmi, M., Ahmad, R., Carretero-Molina, D., Pérez-Victoria, I., Martín, J., Reyes, F., Genilloud, O., Gourbeyre, L., Gefflaut, T., Carlsson, H., Maklakov, A., Field, R. A., O'Neill, E., Wilkinson, B., O'Connell, M., & Ganesan, A. (2022). Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis. Angewandte Chemie International Edition, 61(23), Article e202203175. https://doi.org/10.1002/anie.202203175

By limiting the nitrogen source to glutamic acid, we isolated cyclic peptides from Euglena gracilis containing asparagine and non-proteinogenic amino acids. Structure elucidation was accomplished through spectroscopic methods, mass spectrometry and c... Read More about Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis.