Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo
(2022)
Journal Article
Anane-Adjei, A. B., Fletcher, N. L., Cavanagh, R. J., Houston, Z. H., Crawford, T., Pearce, A. K., Taresco, V., Ritchie, A. A., Clarke, P. A., Grabowska, A. M., Gellert, P. R., Ashford, M. B., Kellam, B., Thurecht, K. J., & Alexander, C. (2022). Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo. Biomaterials Science, 10(9), 2328-2344. https://doi.org/10.1039/d1bm01548f
Hyperbranched polymers have many promising features for drug delivery, owing to their ease of synthesis, multiple functional group content, and potential for high drug loading with retention of solubility. Here we prepared hyperbranched N-(2-hydroxyp... Read More about Synthesis, characterisation and evaluation of hyperbranched N-(2-hydroxypropyl) methacrylamides for transport and delivery in pancreatic cell lines in vitro and in vivo.