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Outputs (139)

Antimicrobial use practices and opinions of beef farmers in England and Wales (2020)
Journal Article
Doidge, C., Hudson, C. D., Burgess, R., Lovatt, F., & Kaler, J. (2020). Antimicrobial use practices and opinions of beef farmers in England and Wales. Veterinary Record, 187(12), e119-e119. https://doi.org/10.1136/vr.105878

© British Veterinary Association. Background Limited research exists on antimicrobial use practices of beef farmers. This study aimed to investigate antimicrobial practices and perceptions of beef farmers in England and Wales, and identify drivers of... Read More about Antimicrobial use practices and opinions of beef farmers in England and Wales.

Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells (2020)
Journal Article
Elsheikha, H. M., Alkurashi, M., Palfreman, S., Castellanos, M., Kong, K., Ning, E., …MacNaughtan, W. (2020). Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells. Pathogens, 9(9), Article 710. https://doi.org/10.3390/pathogens9090710

In this work, the effects of the protozoan Neospora caninum on the bioenergetics, chemical composition, and elemental content of human brain microvascular endothelial cells (hBMECs) were investigated. We showed that N. caninum can impair cell mitocho... Read More about Impact of neospora caninum infection on the bioenergetics and transcriptome of cerebrovascular endothelial cells.

ATP synthase and Alzheimer's disease: putting a spin on the mitochondrial hypothesis (2020)
Journal Article
Ebanks, B., Ingram, T. L., & Chakrabarti, L. (2020). ATP synthase and Alzheimer's disease: putting a spin on the mitochondrial hypothesis. Aging, 12(6), 16647—16662. https://doi.org/10.18632/aging.103867

It is estimated that over 44 million people across the globe have dementia, and half of these cases are believed to be Alzheimer's disease (AD). As the proportion of the global population which is over the age 60 increases so will the number of indiv... Read More about ATP synthase and Alzheimer's disease: putting a spin on the mitochondrial hypothesis.

Cryo-FIB-lift-out: practically impossible to practical reality (2020)
Journal Article
Parmenter, C. D., & Nizamudeen, Z. A. (2020). Cryo-FIB-lift-out: practically impossible to practical reality. Journal of Microscopy, https://doi.org/10.1111/jmi.12953

© 2020 The Authors. Journal of Microscopy published by John Wiley & Sons Ltd on behalf of Royal Microscopical Society In this paper, we explore the development of the Cryo-Lift-Out (cryo-LO) technique as preparation tool for cryogenic transmission... Read More about Cryo-FIB-lift-out: practically impossible to practical reality.

Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research (2020)
Journal Article
McAloon, C., Collins, Á., Hunt, K., Barber, A., Byrne, A. W., Butler, F., …More, S. J. (2020). Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research. BMJ Open, 10(8), Article e039652. https://doi.org/10.1136/bmjopen-2020-039652

Objectives: The aim of this study was to conduct a rapid systematic review and meta-analysis of estimates of the incubation period of COVID-19.

Design: Rapid systematic review and meta-analysis of observational research.

Setting: International... Read More about Incubation period of COVID-19: a rapid systematic review and meta-analysis of observational research.

Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius (2020)
Journal Article
Brown, H. L., Metters, G., Hitchings, M. D., Wilkinson, T. S., Sousa, L., Cooper, J., …Jenkins, R. (2020). Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius. Applied and Environmental Microbiology, 86(20), Article e01768-20. https://doi.org/10.1128/aem.01768-20

Staphylococcus pseudintermedius causes opportunistic infections in dogs. It also has significant zoonotic potential, with the emergence of multidrug-resistance leading to difficulty treating both animal and human infections. Manuka honey has previous... Read More about Antibacterial and anti-virulence activity of manuka honey against genetically diverse Staphylococcus pseudintermedius.

Farmers' Perceptions of Preventing Antibiotic Resistance on Sheep and Beef Farms: Risk, Responsibility, and Action (2020)
Journal Article
Doidge, C., Ruston, A., Lovatt, F., Hudson, C., King, L., & Kaler, J. (2020). Farmers' Perceptions of Preventing Antibiotic Resistance on Sheep and Beef Farms: Risk, Responsibility, and Action. Frontiers in Veterinary Science, 7, Article 524. https://doi.org/10.3389/fvets.2020.00524

© 2020 Doidge, Ruston, Lovatt, Hudson, King and Kaler.

Antibiotic resistance is one of the most serious public health risks facing humanity. The overuse of antibiotics in the treatment of infectious disease have been identified as sources of the... Read More about Farmers' Perceptions of Preventing Antibiotic Resistance on Sheep and Beef Farms: Risk, Responsibility, and Action.

Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza (2020)
Journal Article
Scott, C., Kankanala, J., Foster, T. L., Goldhill, D. H., Bao, P., Simmons, K., …Griffin, S. (2020). Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza. PLoS Pathogens, 16(8), Article e1008716. https://doi.org/10.1371/journal.ppat.1008716

Pandemic influenza A virus (IAV) remains a significant threat to global health. Preparedness relies primarily upon a single class of neuraminidase (NA) targeted antivirals, against which resistance is steadily growing. The M2 proton channel is an alt... Read More about Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza.

Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain) (2020)
Journal Article
Jurado-Tarifa, E., Cano-Terriza, D., Daly, J. M., Arenas, A., & García-Bocanegra, I. (2020). Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain). Zoonoses and Public Health, 67(8), 869-875. https://doi.org/10.1111/zph.12758

In April 2009, a new influenza A virus (IAV) subtype (A(H1N1)pdm09) spread worldwide and triggered the first human influenza pandemic of the 21st century. Since then, exposure to the pandemic H1N1 IAV has been confirmed in different animal species. S... Read More about Serosurvey of pandemic H1N1 influenza A virus in dogs in Andalusia (southern Spain).