Outputs (139)

Significant transcriptional changes in mature daughter Varroa destructor mites during infestation of different developmental stages of honeybees (2020)
Journal Article
Tu, Y., Wu, J., Elsheikha, H. M., Getachew, A., Zhou, C., Zhou, H., & Xu, S. (2020). Significant transcriptional changes in mature daughter Varroa destructor mites during infestation of different developmental stages of honeybees. Pest Management Science, 76(8), 2736-2745. https://doi.org/10.1002/ps.5821

Background: Varroa destructor is considered a major cause of honeybee (Apis mellifera) colony losses worldwide. Although V. destructor mites exhibit preference behavior for certain honeybee lifecycle stages, the mechanism underlying host finding and... Read More about Significant transcriptional changes in mature daughter Varroa destructor mites during infestation of different developmental stages of honeybees.

Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia (2020)
Journal Article
Fabijan, J., Sarker, N., Speight, N., Owen, H., Meers, J., Simmons, G., …Trott, D. J. (2020). Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia. Journal of Comparative Pathology, 176, 50-66. https://doi.org/10.1016/j.jcpa.2020.02.003

© 2020 Elsevier Ltd Koala retrovirus (KoRV) infection shows differences in prevalence and load between northern and southern Australian koala populations; however, the effect of this on diseases such as lymphoma and chlamydial disease is unclear. Thi... Read More about Pathological Findings in Koala Retrovirus-positive Koalas (Phascolarctos cinereus) from Northern and Southern Australia.

Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom (2020)
Journal Article
Guardone, L., Ebani, V. V., Verin, R., Nardoni, S., Consolazione, A., Bennett, M., & Mancianti, F. (2020). Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom. Animals, 10(3), Article 446. https://doi.org/10.3390/ani10030446

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Arthropod-borne diseases (ABD) are of increasing interest in veterinary and public health. Eurasian badgers (Meles meles) are known to harbor a wide range of pathogens, but information on thei... Read More about Molecular detection of arthropod-borne pathogens in Eurasian badgers (Meles meles) from the United Kingdom.

Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism (2020)
Journal Article
Boag, A. M., Short, A., Kennedy, L. J., Syme, H., Graham, P. A., & Catchpole, B. (2020). Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism. Canine Medicine and Genetics, 7, Article 2. https://doi.org/10.1186/s40575-020-0081-4

Background
Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison’s disease in humans. Several dog breeds are overrepresented in the disease population, suggesting t... Read More about Polymorphisms in the CTLA4 promoter sequence are associated with canine hypoadrenocorticism.

Update on caseous lymphadenitis in sheep (2020)
Journal Article
Gascoigne, E., Ogden, N., Lovatt, F., & Davies, P. (2020). Update on caseous lymphadenitis in sheep. In Practice, 42(2), 105-114. https://doi.org/10.1136/inp.m455

Background: Caseous lymphadenitis (CLA), caused by the gram-positive bacteria Corynebacterium pseudotuberculosis, has been present in Great Britain since the 1980s and is now considered endemic. CLA is considered to be an iceberg disease; that is, it... Read More about Update on caseous lymphadenitis in sheep.

RHΔgra17Δnpt1 strain of Toxoplasma gondii elicits protective immunity against acute, chronic and congenital toxoplasmosis in mice (2020)
Journal Article
Sun, L., Liang, Q., Elsheikha, H. M., Cao, X., Nie, L., Li, T., …Wang, J. (2020). RHΔgra17Δnpt1 strain of Toxoplasma gondii elicits protective immunity against acute, chronic and congenital toxoplasmosis in mice. Microorganisms, 8(3), Article 352. https://doi.org/10.3390/microorganisms8030352

In the present study, a dense granule protein 17 (gra17) and novel putative transporter (npt1) double deletion mutant of Toxoplasma gondii RH strain was engineered. The protective efficacy of vaccination using RHΔgra17Δnpt1 tachyzoites against acute,... Read More about RHΔgra17Δnpt1 strain of Toxoplasma gondii elicits protective immunity against acute, chronic and congenital toxoplasmosis in mice.

Single dose epidural methylprednisolone as a treatment and predictor of outcome following subsequent decompressive surgery in degenerative lumbosacral stenosis with foraminal stenosis (2020)
Journal Article
Gomes, S. A., Lowrie, M., & Targett, M. (2020). Single dose epidural methylprednisolone as a treatment and predictor of outcome following subsequent decompressive surgery in degenerative lumbosacral stenosis with foraminal stenosis. Veterinary Journal, 257, Article 105451. https://doi.org/10.1016/j.tvjl.2020.105451

© 2020 Elsevier Ltd Alternative treatments to surgery in canine degenerative lumbosacral stenosis (DLSS) remain limited and reliable predictors of outcome are lacking. The aims of this clinical trial were threefold: to assess the usefulness of single... Read More about Single dose epidural methylprednisolone as a treatment and predictor of outcome following subsequent decompressive surgery in degenerative lumbosacral stenosis with foraminal stenosis.

Renal accumulation of prooxidant mineral elements and CKD in domestic cats (2020)
Journal Article
Alborough, R., Grau-Roma, L., de Brot, S., Hantke, G., Vazquez, S., & Gardner, D. S. (2020). Renal accumulation of prooxidant mineral elements and CKD in domestic cats. Scientific Reports, 10(1), Article 3160. https://doi.org/10.1038/s41598-020-59876-6

Felids have a high incidence of chronic kidney disease (CKD), for which the most common renal lesion is chronic interstitial nephritis (CIN). CIN can be induced by tissue oxidative stress, which is determined by the cellular balance of pro- and anti-... Read More about Renal accumulation of prooxidant mineral elements and CKD in domestic cats.

Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers (2020)
Journal Article
Janssen, E. A., Ogden, A., Bhattarai, S., Sahoo, B., Mongan, N. P., Alsaleem, M., …Aneja, R. (2020). Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers. Scientific Reports, 10(1), Article 3009. https://doi.org/10.1038/s41598-020-59514-1

© 2020, The Author(s). Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in HER3;... Read More about Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers.

Transcriptional changes in Toxoplasma gondii in response to treatment with monensin (2020)
Journal Article
Zhai, B., He, J., Elsheikha, H. M., Li, J., Zhu, X., & Yang, X. (2020). Transcriptional changes in Toxoplasma gondii in response to treatment with monensin. Parasites and Vectors, 13, Article 84. https://doi.org/10.1186/s13071-020-3970-1

Background: Infection with the apicomplexan protozoan parasite T. gondii can cause severe and potentially fatal cerebral and ocular disease, especially in immunocompromised individuals. The anticoccidial ionophore drug monensin has been shown to have... Read More about Transcriptional changes in Toxoplasma gondii in response to treatment with monensin.