Skip to main content

Research Repository

Advanced Search

Outputs (144)

GaitKeeper: a system for measuring canine gait (2017)
Journal Article
Ladha, C., O’Sullivan, J., Belshaw, Z., & Asher, L. (2017). GaitKeeper: a system for measuring canine gait. Sensors, 17(2), https://doi.org/10.3390/s17020309

It is understood gait has the potential to be used as a window into neurodegenerative disorders, identify markers of subclinical pathology, inform diagnostic algorithms of disease progression and measure the efficacy of interventions. Dogs’ gaits are... Read More about GaitKeeper: a system for measuring canine gait.

In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification (2017)
Journal Article
O'Connor, M., Bishop, K., Workman, R. G., Maddison, B. C., & Gough, K. C. (in press). In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification. Prion, 11(1), 54-64. https://doi.org/10.1080/19336896.2016.1259051

The in vitro amplification of prions by serial protein misfolding cyclic amplification has been shown to detect PrPSc to levels at least as sensitive as rodent bioassay but in a fraction of the time. Bovine spongiform encephalopathy is a zoonotic pri... Read More about In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification.

Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer (2017)
Journal Article
Shafiee, M. N., Mongan, N. P., Seedhouse, C., Chapman, C., Deen, S., Abu, J., & Atiomo, W. (2017). Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer. Acta Obstetricia et Gynecologica Scandinavica, 96(5), 556-562. https://doi.org/10.1111/aogs.13106

Introduction: Women with polycystic ovary syndrome (PCOS) have a 3-fold higher risk of endometrial cancer (EC). Insulin resistance and hyperlipidaemia may be pertinent factors in the pathogenesis of both conditions. The aim of this study was to inves... Read More about Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer.

‘Doing good by proxy’: Human-animal kinship and the ‘donation’ of canine blood (2017)
Journal Article
Ashall, V., & Hobson-West, P. (in press). ‘Doing good by proxy’: Human-animal kinship and the ‘donation’ of canine blood. Sociology of Health and Illness, 39(6), https://doi.org/10.1111/1467-9566.12534

This paper demonstrates the relevance of animals to medical sociology by arguing that pet owners’ accounts of veterinary decision-making can highlight key sociological themes which have important relevance to both human and animal health. Based on se... Read More about ‘Doing good by proxy’: Human-animal kinship and the ‘donation’ of canine blood.

M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China (2017)
Journal Article
Pu, J., Sun, H., Qu, Y., Wang, C., Gao, W., Zhu, J., …Liu, J. (2017). M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China. Journal of Virology, 91(8), Article e02055-16. https://doi.org/10.1128/JVI.02055-16

Segment reassortment and base mutagenesis of influenza A viruses are the primary routes to the rapid evolution of high fitness virus genotypes. We recently described a predominant G57 genotype of avian H9N2 viruses that caused country-wide outbreaks... Read More about M gene reassortment in H9N2 influenza virus promotes early infection and replication: contribution to rising virus prevalence in chickens in China.

A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion (2017)
Journal Article
White, K. L., Paine, S., & Harris, J. (2017). A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion. Veterinary Anaesthesia and Analgesia, 44(4), https://doi.org/10.1016/j.vaa.2017.01.001

Objective: To characterise, as a clinical study, the pharmacokinetics and pharmacodynamics and describe the hypnotic effect of the neurosteroid alfaxalone (3α-hydroxy-5 α-pregnane-11, 20-dione) formulated with 2-hydroxypropyl-β-cyclodextrin in male a... Read More about A clinical evaluation of the pharmacokinetics and pharmacodynamics of intravenous alfaxalone in cyclodextrin in male and female rats following a loading dose and constant rate infusion.

Climate change and cattle farming (2017)
Journal Article
Statham, J. M., Green, M. J., Husband, J., & Huxley, J. (2017). Climate change and cattle farming. In Practice, 39(1), https://doi.org/10.1136/inp.j195

Issues raised by cattle farming in relation to climate change extend beyond discussion of greenhouse gas emissions and global warming. There are profound consequences for water availability, soil degradation, biodiversity and local ecology, as well a... Read More about Climate change and cattle farming.

Concurrent infection of bluetongue and peste-des-petits-ruminants virus in small ruminants in Haryana State of India (2017)
Journal Article
Maan, S., Kumar, A., Gupta, A. K., Dalal, A., Chaudhary, D., Gupta, T. K., …Mertens, P. P. (2018). Concurrent infection of bluetongue and peste-des-petits-ruminants virus in small ruminants in Haryana State of India. Transboundary and Emerging Diseases, 65(1), 235-239. https://doi.org/10.1111/tbed.12610

Bluetongue (BT) and peste-des-petits-ruminants (PPR) are major transboundary diseases of small ruminant, which are endemic in India. Testing of bluetongue virus (BTV) and peste-des-petits-ruminants virus (PPRV) from recent outbreaks (2015–2016) in di... Read More about Concurrent infection of bluetongue and peste-des-petits-ruminants virus in small ruminants in Haryana State of India.

The impact of competition on elephant musth strategies: a game–theoretic model (2017)
Journal Article
Wyse, J. M., Hardy, I. C., Yon, L., & Mesterton-Gibbons, M. (in press). The impact of competition on elephant musth strategies: a game–theoretic model. Journal of Theoretical Biology, https://doi.org/10.1016/j.jtbi.2017.01.025

Mature male African Savannah elephants are known to periodically enter a temporary state of heightened aggression called “musth,” often linked with increased androgens, particularly testosterone. Sexually mature males are capable of entering musth at... Read More about The impact of competition on elephant musth strategies: a game–theoretic model.

Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers (2017)
Journal Article
Mahendran, S., Huxley, J., Chang, Y.-M., Burnell, M., Barrett, D., Whay, H., …Bell, N. (2017). Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers. Veterinary Journal, 220, https://doi.org/10.1016/j.tvjl.2017.01.011

The objective of this study was to assess both independent and combined effects of routine foot trimming of heifers at 3 weeks pre-calving and 100 days post calving on the first lactation lameness and lactation productivity. A total of 419 pre-calvin... Read More about Randomised controlled trial to evaluate the effect of foot trimming before and after first calving on subsequent lameness episodes and productivity in dairy heifers.