Outputs (139)

A method for extracting electronic patient record data from practice management software systems used in veterinary practice (2016)
Journal Article
Jones-Diette, J. S., Brennan, M. L., Cobb, M., Doit, H., & Dean, R. S. (in press). A method for extracting electronic patient record data from practice management software systems used in veterinary practice. BMC Veterinary Research, 12(239), https://doi.org/10.1186/s12917-016-0861-y

Background Data extracted from electronic patient records (EPRs) within practice management software systems are increasingly used in veterinary research. The use of real patient data gives the potential to generate research that can readily be appl... Read More about A method for extracting electronic patient record data from practice management software systems used in veterinary practice.

Modulation of the immune response to Mycobacterium tuberculosis during malaria/M. tuberculosis co-infection (2016)
Journal Article
Chukwuanukwu, R. C., Onyenekwe, C. C., Martinez-Pomares, L., Flynn, R. J., Singh, S., Amilo, G. I., …Okoye, J. O. (in press). Modulation of the immune response to Mycobacterium tuberculosis during malaria/M. tuberculosis co-infection. Clinical and Experimental Immunology, 187(2), https://doi.org/10.1111/cei.12861

Tuberculosis (TB) causes significant morbidity and mortality on a global scale. The African region has 24% of the world's TB cases. TB overlaps with other infectious diseases such as malaria and HIV, which are also highly prevalent in the African reg... Read More about Modulation of the immune response to Mycobacterium tuberculosis during malaria/M. tuberculosis co-infection.

Global population divergence and admixture of the brown rat (Rattus norvegicus) (2016)
Journal Article
Puckett, E. E., Park, J., Combs, M., Blum, M. J., Bryant, J. E., Caccone, A., …Munshi-South, J. (2016). Global population divergence and admixture of the brown rat (Rattus norvegicus). Proceedings of the Royal Society B: Biological Sciences, 283(1841), Article 20161762. https://doi.org/10.1098/rspb.2016.1762

Native to China and Mongolia, the brown rat (Rattus norvegicus) now enjoys a worldwide distribution. While black rats and the house mouse tracked the regional development of human agricultural settlements, brown rats did not appear in Europe until th... Read More about Global population divergence and admixture of the brown rat (Rattus norvegicus).

A sensitive 301V BSE serial PMCA assay (2016)
Journal Article
Gough, K. C., Bishop, K., Somerville, R. A., Hunter, N., & Maddison, B. C. (2016). A sensitive 301V BSE serial PMCA assay. F1000Research, 5(2529), https://doi.org/10.12688/f1000research.9735.1

The prion strain 301V, is a mouse passaged form of bovine spongiform encephalopathy (BSE). It has been used as a model of BSE for more than 20 years, in particular in the investigation of tissue distribution of infectivity, the molecular phenotype an... Read More about A sensitive 301V BSE serial PMCA assay.

The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport (2016)
Journal Article
Daniel, Z., Swali, A., Emes, R. D., & Langley-Evans, S. C. (2016). The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport. Genes and Nutrition, 11(27), https://doi.org/10.1186/s12263-016-0541-3

Fetal exposure to a maternal low protein diet during rat pregnancy is associated with hypertension, renal dysfunction and metabolic disturbance in adult life. These effects are present when dietary manipulations target only the first half of pregnanc... Read More about The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up-regulates cholesterol transport.

Exploring attitudes and beliefs towards implementing cattle disease prevention and control measures: a qualitative study with dairy farmers in Great Britain (2016)
Journal Article
Brennan, M. L., Wright, N., Wapenaar, W., Jarratt, S., Hobson-West, P., Richens, I. F., …O’Connor, H. M. (in press). Exploring attitudes and beliefs towards implementing cattle disease prevention and control measures: a qualitative study with dairy farmers in Great Britain. Animals, 6(10), Article 61. https://doi.org/10.3390/ani6100061

Disease prevention and control practices are frequently highlighted as important to ensure the health and welfare of farmed animals, although little is known as to why not many practices are carried out. The aim of this study was to identify the moti... Read More about Exploring attitudes and beliefs towards implementing cattle disease prevention and control measures: a qualitative study with dairy farmers in Great Britain.

Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration (2016)
Journal Article
Pollard, A., Shephard, F., Freed, J., Liddell, S., & Chakrabarti, L. (2016). Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration. Aging, 8(10), 2425-2436. https://doi.org/10.18632/aging.101064

Carbonic anhydrase inhibitors are used to treat glaucoma and cancers. Carbonic anhydrases perform a crucial role in the conversion of carbon dioxide and water into bicarbonate and protons. However, there is little information about carbonic anhydrase... Read More about Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration.

Malignant inflammation in cutaneous T-cell lymphoma: a hostile takeover (2016)
Journal Article
Krejsgaard, T., Lindahl, L. M., Mongan, N. P., Wasik, M. A., Litvinov, I. V., Iversen, L., …Odum, N. (in press). Malignant inflammation in cutaneous T-cell lymphoma: a hostile takeover. Seminars in Immunopathology, https://doi.org/10.1007/s00281-016-0594-9

Cutaneous T-cell lymphomas (CTCL) are characterized by the presence of chronically inflamed skin lesions containing malignant T cells. Early disease presents as limited skin patches or plaques and exhibits an indolent behavior. For many patients, the... Read More about Malignant inflammation in cutaneous T-cell lymphoma: a hostile takeover.

A systematic review of the literature relating to captive great ape morbidity and mortality (2016)
Journal Article
Strong, V. J., Grindlay, D. J., Redrobe, S., Cobb, M., & White, K. (2016). A systematic review of the literature relating to captive great ape morbidity and mortality. Journal of Zoo and Wildlife Medicine, 47(3), https://doi.org/10.1638/2015-0240.1

Wild bonobos (Pan paniscus), chimpanzees (Pan troglodytes), Western gorillas (Gorilla gorilla), and orangutans (Pongo pygmaeus, Pongo abelii) are threatened with extinction. In order to help maintain a self-sustaining zoo population, clinicians requi... Read More about A systematic review of the literature relating to captive great ape morbidity and mortality.

Equine hepatocytes: isolation, cryopreservation, and applications to in vitro drug metabolism studies (2016)
Journal Article
Shibany, K. A., Tötemeyer, S., Pratt, S. L., & Paine, S. W. (2016). Equine hepatocytes: isolation, cryopreservation, and applications to in vitro drug metabolism studies. Pharmacology Research and Perspectives, 4(5), 1-8. https://doi.org/10.1002/prp2.268

Despite reports of the successful isolation of primary equine hepatocytes, thereare no published data regarding the successful cryopreservation of these isolatedcells. In this study, a detailed description of the procedures for isolation, cryop-reser... Read More about Equine hepatocytes: isolation, cryopreservation, and applications to in vitro drug metabolism studies.