Outputs (105)

Diversity of group A rotavirus on a UK pig farm (2015)
Journal Article
Chandler-Bostock, R., Hancox, L., Payne, H., Iturriza-Gomara, M., Daly, J. M., & Mellits, K. (2015). Diversity of group A rotavirus on a UK pig farm. Veterinary Microbiology, 180(3-4), 205-211. https://doi.org/10.1016/j.vetmic.2015.09.009

Group A rotaviruses (GARV) are a significant cause of enteritis in young pigs. The aim of this study was to extend our understanding of the molecular epidemiology of porcine GARV in the UK by investigating the genetic diversity of GARV on a conventio... Read More about Diversity of group A rotavirus on a UK pig farm.

Detection of viable Mycobacterium avium subspecies paratuberculosis in powdered infant formula by phage-PCR and confirmed by culture (2015)
Journal Article

VEGF and LPS synergistically silence inflammatory response to Plasmodium berghei infection and protect against cerebral malaria (2015)
Journal Article
Canavese, M., Dottorini, T., & Crisanti, A. (2015). VEGF and LPS synergistically silence inflammatory response to Plasmodium berghei infection and protect against cerebral malaria. Pathogens and Global Health, 109(6), https://doi.org/10.1179/2047773215Y.0000000018

Malaria infection induces, alongside endothelial damage and obstruction hypoxia, a potent inflammatory response similar to that observed in other systemic diseases caused by bacteria and viruses. Accordingly, it is increasingly recognised that cerebr... Read More about VEGF and LPS synergistically silence inflammatory response to Plasmodium berghei infection and protect against cerebral malaria.

Extended 2D myotube culture recapitulates postnatal fibre type plasticity (2015)
Journal Article
Sebastian, S., Goulding, L., Kuchipudi, S. V., & Chang, K.-C. (in press). Extended 2D myotube culture recapitulates postnatal fibre type plasticity. BMC Cell Biology, 16(1), https://doi.org/10.1186/s12860-015-0069-1

Background: The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the ability of myotubes to undergo... Read More about Extended 2D myotube culture recapitulates postnatal fibre type plasticity.

Objects in contact with classical scrapie sheep act as a reservoir for scrapie transmission (2015)
Journal Article
Konold, T., Hawkins, S. A., Thurston, L. C., Maddison, B. C., Gough, K. C., Duarte, A., & Simmons, H. A. (2015). Objects in contact with classical scrapie sheep act as a reservoir for scrapie transmission. Frontiers in Veterinary Science, 2, Article 32. https://doi.org/10.3389/fvets.2015.00032

Classical scrapie is an environmentally transmissible prion disease of sheep and goats. Prions can persist and remain potentially infectious in the environment for many years and thus pose a risk of infecting animals after re-stocking. In vitro studi... Read More about Objects in contact with classical scrapie sheep act as a reservoir for scrapie transmission.

Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer (2015)
Journal Article
Kitchen, M. O., Bryan, R. T., Haworth, K. E., Emes, R. D., Luscombe, C., Gommersall, L., …Farrell, W. E. (2015). Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer. PLoS ONE, 10(9), e0137003. https://doi.org/10.1371/journal.pone.0137003

Introduction

Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous reports of DNA methylation in low/intermediate grade non-muscle invasive bladd... Read More about Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer.

PA-X is a virulence factor in avian H9N2 influenza virus (2015)
Journal Article
Gao, H., Liu, J., Kong, W., Sun, H., Pu, J., Chang, K.-C., …Wang, J. (2015). PA-X is a virulence factor in avian H9N2 influenza virus. Journal of General Virology, 96(9), https://doi.org/10.1099/jgv.0.000232

H9N2 influenza viruses have been circulating worldwide in multiple avian species, and regularly infect pigs and humans. Recently, a novel protein, PA-X, produced from the PA gene by ribosomal frameshifting, was demonstrated to be an antivirulence fac... Read More about PA-X is a virulence factor in avian H9N2 influenza virus.

Histologic, immunohistochemical, and electron microscopic characterization of a malignant iridophoroma in a dwarf bearded dragon (Pogona henrylawsoni) (2015)
Journal Article
de Brot, S., Sydler, T., Nufer, L., & Ruetten, M. (2015). Histologic, immunohistochemical, and electron microscopic characterization of a malignant iridophoroma in a dwarf bearded dragon (Pogona henrylawsoni). Journal of Zoo and Wildlife Medicine, 46(3), https://doi.org/10.1638/2013-0113.1

A dwarf bearded dragon (Pogona henrylawsoni) was presented with a whitish subcutaneous mandibular mass and multiple nodules in the oral mucosa, heart, liver, kidney, intestine and visceral fat. Histologically, the tumor consisted of densely packed sp... Read More about Histologic, immunohistochemical, and electron microscopic characterization of a malignant iridophoroma in a dwarf bearded dragon (Pogona henrylawsoni).

Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma (2015)
Journal Article
Sibbesen, N. A., Kopp, K. L., Litvinov, I. V., Jønson, L., Willerslev-Olsen, A., Fredholm, S., …Odum, N. (2015). Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma. Oncotarget, 6(24),

Aberrant activation of Janus kinase-3 (Jak3) and its key down-stream effectors, Signal Transducer and Activator of Transcription-3 (STAT3) and STAT5, is a key feature of malignant transformation in cutaneous T-cell lymphoma (CTCL). However, it remain... Read More about Jak3, STAT3, and STAT5 inhibit expression of miR-22, a novel tumor suppressor microRNA, in cutaneous T-Cell lymphoma.

Recycling manure as cow bedding: potential benefits and risks for UK dairy farms (2015)
Journal Article
Lech, K. A., Archer, S. C., Breen, J. E., Green, M. J., Ohnstad, I. C., Tuer, S., & Bradley, A. J. (in press). Recycling manure as cow bedding: potential benefits and risks for UK dairy farms. Veterinary Journal, 206(2), https://doi.org/10.1016/j.tvjl.2015.08.013

Material obtained from physical separation of slurry (recycled manure solids; RMS) has been used as bedding for dairy cows in dry climates in the US since the 1970s. Relatively recently, the technical ability to produce drier material has led to adop... Read More about Recycling manure as cow bedding: potential benefits and risks for UK dairy farms.