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Addressing Ethnicity in the Design and Evaluation of an Educational Intervention on Interindividual Variation in Pharmacokinetics (2025)
Journal Article
Koenig, J. A., Olafuyi, O., & Patel, R. (2025). Addressing Ethnicity in the Design and Evaluation of an Educational Intervention on Interindividual Variation in Pharmacokinetics. Pharmacology Research and Perspectives, 13(1), Article e70073. https://doi.org/10.1002/prp2.70073

Interindividual variation in pharmacokinetics can occur due to diet, environmental or lifestyle factors, underlying pathology, and gene variants, typically single nucleotide polymorphisms (SNPs). Genetic mechanisms have received the most attention in... Read More about Addressing Ethnicity in the Design and Evaluation of an Educational Intervention on Interindividual Variation in Pharmacokinetics.

Clinico-pathological features predicting indication to mastectomy in breast cancer patients achieving complete response after neoadjuvant therapy: a retrospective analysis of the EUSOMA database (2025)
Journal Article
Catanuto, G., Gentile, D., Martorana, F., Tomatis, M., Ponti, A., Marotti, L., Aristei, C., Cardoso, M. J., Cheung, K. L., Curigliano, G., De Vries, J., Karakatsanis, A., Santini, D., Sardanelli, F., Van Dam, P., Rubio, I. T., & EUSOMA Working Group. (2025). Clinico-pathological features predicting indication to mastectomy in breast cancer patients achieving complete response after neoadjuvant therapy: a retrospective analysis of the EUSOMA database. EJSO - European Journal of Surgical Oncology, 51(6), Article 109643. https://doi.org/10.1016/j.ejso.2025.109643

Aims: We investigated factors related to the type of surgery, i.e. mastectomy versus breast conserving surgery (BCS), in breast cancer (BC) patients with complete pathologic response in the breast (ypT0) after neoadjuvant therapy (NAT). Methods: A re... Read More about Clinico-pathological features predicting indication to mastectomy in breast cancer patients achieving complete response after neoadjuvant therapy: a retrospective analysis of the EUSOMA database.

The impact of an educational intervention on undergraduate students’ knowledge, acceptability, and willingness to pay for dapivirine vaginal ring in Nigeria's first indigenous university: a single-arm, non-randomized study (2025)
Journal Article
Isah, A., Ezenri, G., Obi, O., Okibe, N. A., Ma’aji, H. U., Ugochukwu, E. J., Eze, C. C., Amoke, C. M., Ezeodimegwu, A., Idabor, C. C., Abubakar, M. M., Iloabuchi, F., Ugwu, I. J., Asogwa, C. M., Ukwe, C. V., & Ukoha-kalu, B. O. (2025). The impact of an educational intervention on undergraduate students’ knowledge, acceptability, and willingness to pay for dapivirine vaginal ring in Nigeria's first indigenous university: a single-arm, non-randomized study. Discover Social Science and Health, 5(1), Article 8. https://doi.org/10.1007/s44155-025-00153-0

Background: This study aimed to assess the impact of an educational intervention on knowledge, acceptability, and willingness to pay (WTP) for dapivirine vaginal ring (DPV-VR) by undergraduate female students at the University of Nigeria (UNN). Metho... Read More about The impact of an educational intervention on undergraduate students’ knowledge, acceptability, and willingness to pay for dapivirine vaginal ring in Nigeria's first indigenous university: a single-arm, non-randomized study.

Updates and Future Directions for the Nottingham Research Programme on Primary Breast Cancer in Older Women (2025)
Journal Article
Parks, R. M., & Cheung, K.-L. (2025). Updates and Future Directions for the Nottingham Research Programme on Primary Breast Cancer in Older Women. Cancers, 17(3), Article 346. https://doi.org/10.3390/cancers17030346

The global population is ageing and the risk of breast cancer increases with age. Therefore, we can expect an increase in the number of cases of breast cancer worldwide in the next 20 years. Currently, there are few age-specific guidelines for the ma... Read More about Updates and Future Directions for the Nottingham Research Programme on Primary Breast Cancer in Older Women.

Chlorpyrifos Acts as a Positive Modulator and an Agonist of N-Methyl-d-Aspartate (NMDA) Receptors: A Novel Mechanism of Chlorpyrifos-Induced Neurotoxicity (2025)
Journal Article
Sherif, M. A., Carter, W. G., & Mellor, I. R. (2025). Chlorpyrifos Acts as a Positive Modulator and an Agonist of N-Methyl-d-Aspartate (NMDA) Receptors: A Novel Mechanism of Chlorpyrifos-Induced Neurotoxicity. Journal of Xenobiotics, 15(1), Article 12. https://doi.org/10.3390/jox15010012

Chlorpyrifos (CPF) is a broad-spectrum organophosphate insecticide. Long-term exposure to low levels of CPF is associated with neurodevelopmental and neurodegenerative disorders. The mechanisms leading to these effects are still not fully understood... Read More about Chlorpyrifos Acts as a Positive Modulator and an Agonist of N-Methyl-d-Aspartate (NMDA) Receptors: A Novel Mechanism of Chlorpyrifos-Induced Neurotoxicity.

Evaluating student understanding of core pharmacokinetic concepts (2025)
Journal Article
Babey, A.-M., Koenig, J., Cunningham, M., Shield, A., Restini, C., Djouma, E., Mraiche, F., Mifsud, J., Kelly, J. P., Nicolazzo, J., Karpa, K. J., Volbrecht, K., Santiago, M. J., Hawes, M., Aljofan, M., Kelly-Laubscher, R., Karunaratne, N., Tucker, S. J., Hinton, T., Liang, W., …White, P. J. (2025). Evaluating student understanding of core pharmacokinetic concepts. European Journal of Pharmacology, 990, Article 177256. https://doi.org/10.1016/j.ejphar.2025.177256

Both educators and graduates have expressed concern about a perceived pharmacology knowledge gap that includes difficulty applying fundamental principles to clinical and research problems. Consequently, we sought to determine the extent to which curr... Read More about Evaluating student understanding of core pharmacokinetic concepts.

Evaluating student understanding of pharmacodynamics core concepts (2025)
Journal Article
Kelly-Laubscher, R., Koenig, J., Cunningham, M., Aljofan, M., Babey, A.-M., Hawes, M., Hinton, T., Karpa, K., Karunaratne, N., Nicolazzo, J., Liang, W., Mraiche, F., Restini, C., Santiago, M., Volbrecht, K., Guilding, C., & White, P. J. (2025). Evaluating student understanding of pharmacodynamics core concepts. European Journal of Pharmacology, 990, Article 177257. https://doi.org/10.1016/j.ejphar.2025.177257

Pharmacodynamics is an essential subdiscipline of pharmacology that underpins safe and effective prescribing and therapeutic decision-making, as well as drug discovery and development. The exponential increase in the number of therapeutic drugs has p... Read More about Evaluating student understanding of pharmacodynamics core concepts.

Patient-Reported Outcomes in Geriatric Oncology—Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model (2024)
Journal Article
Francis, J., Baxter, M., Giza, D., Cheung, K.-L., & Parks, R. (2024). Patient-Reported Outcomes in Geriatric Oncology—Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model. Drugs and Aging, 42(1), 1-7. https://doi.org/10.1007/s40266-024-01167-0

Breast cancer remains the most prevalent cancer worldwide, necessitating advancements in its management. Surgery remains the recommended primary treatment although neoadjuvant or adjuvant treatments, such as chemotherapy, may also be indicated. Howev... Read More about Patient-Reported Outcomes in Geriatric Oncology—Balancing Quality of Life and Therapeutic Effectiveness Using Primary Breast Cancer as a Model.

Pharmacists’ knowledge, attitude and practice of HIV post-exposure prophylaxis: a cross-sectional comparative study in two Nigerian teaching hospitals (2024)
Journal Article
Isah, A., Abubakar, M. M., Igboeli, N. U., Ugochukwu, E. J., Aguiyi-Ikeanyi, C. N., Akunne, M. O., Ma’aji, H. U., & Ukoha-Kalu, B. O. (2024). Pharmacists’ knowledge, attitude and practice of HIV post-exposure prophylaxis: a cross-sectional comparative study in two Nigerian teaching hospitals. Discover Public Health, 21(1), Article 237. https://doi.org/10.1186/s12982-024-00357-w

Introduction:

Pharmacists play an important role in HIV post-exposure prophylaxis. This study compared the knowledge, attitude, and practice (KAP) of HIV post-exposure prophylaxis (PEP) among pharmacists practicing in two Nigerian teaching hospit... Read More about Pharmacists’ knowledge, attitude and practice of HIV post-exposure prophylaxis: a cross-sectional comparative study in two Nigerian teaching hospitals.