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Why most published meta-analysis findings are false (2019)
Journal Article
Doleman, B., Williams, J. P., & Lund, J. (2019). Why most published meta-analysis findings are false. Techniques in Coloproctology, 23(9), 925-928. https://doi.org/10.1007/s10151-019-02020-y

Almost a decade after the controversial paper ‘why most published research findings are false’ was written [1], we re-visit this concern with regard to published meta-analyses. Although reading the title of this article may make some pause for though... Read More about Why most published meta-analysis findings are false.

Safety of azithromycin in paediatrics: a systematic review protocol (2019)
Journal Article
Xu, P., Zeng, L., Xiong, T., Choonara, I., Qazi, S., & Zhang, L. (2019). Safety of azithromycin in paediatrics: a systematic review protocol. BMJ Paediatrics Open, 3(1), Article e000469. https://doi.org/10.1136/bmjpo-2019-000469

Introduction: Azithromycin is widely used in children not only in the treatment of individual children with infectious diseases, but also as mass drug administration (MDA) within a community to eradicate or control specific tropical diseases. MDA has... Read More about Safety of azithromycin in paediatrics: a systematic review protocol.

MeMa: Designing the Memory Machine (2019)
Presentation / Conference Contribution
Price, D., Jacobs, R., Darzentas, D., Perez Vallejos, E., Chadborn, N., Martindale, S., & Urquhart, L. (2019). MeMa: Designing the Memory Machine. In Companion Publication of the 2019 on Designing Interactive Systems Conference 2019 Companion (271--276). https://doi.org/10.1145/3301019.3323882

The Memory Machine is an ambitious project that aims to develop a device to capture people's memories to create a blend of personal and factual data that builds identities, and contextualizes personal recollections. The Memory Machine has been guided... Read More about MeMa: Designing the Memory Machine.

A novel transwell blood brain barrier model using primary human cells (2019)
Journal Article
Stone, N. L., England, T. J., & O’Sullivan, S. E. (2019). A novel transwell blood brain barrier model using primary human cells. Frontiers in Cellular Neuroscience, 13, Article 230. https://doi.org/10.3389/fncel.2019.00230

© 2019 Stone, England and O’Sullivan. Structural alterations and breakdown of the blood brain barrier (BBB) is often a primary or secondary consequence of disease, resulting in brain oedema and the transport of unwanted substances into the brain. It... Read More about A novel transwell blood brain barrier model using primary human cells.

Mitochondrial dysfunction causes Ca2+ overload and ECM degradation–mediated muscle damage in C. elegans (2019)
Journal Article
Sudevan, S., Takiura, M., Kubota, Y., Higashitani, N., Cooke, M., Ellwood, R. A., …Higashitani, A. (2019). Mitochondrial dysfunction causes Ca2+ overload and ECM degradation–mediated muscle damage in C. elegans. FASEB Journal, 33(8), 9540-9550. https://doi.org/10.1096/fj.201802298r

Mitochondrial dysfunction impairs muscle health and causes subsequent muscle wasting. This study explores the role of mitochondrial dysfunction as an intramuscular signal for the extracellular matrix (ECM)–based proteolysis and, consequentially, musc... Read More about Mitochondrial dysfunction causes Ca2+ overload and ECM degradation–mediated muscle damage in C. elegans.

Dose and formulation of azithromycin in mass drug administration studies: a systematic review protocol (2019)
Journal Article
Yue, Y., Xiong, T., Zeng, L., Choonara, I., Qazi, S., Chen, H., & Mu, D. (2019). Dose and formulation of azithromycin in mass drug administration studies: a systematic review protocol. BMJ Paediatrics Open, 3(1), Article e000462. https://doi.org/10.1136/bmjpo-2019-000462

Introduction: Azithromycin has been given for tropical infectious diseases such as trachoma and yaws by mass drug administration (MDA). As well as controlling the infectious disease in question, MDA may have a beneficial effect in reducing mortality... Read More about Dose and formulation of azithromycin in mass drug administration studies: a systematic review protocol.

Long-Term Endurance and Power Training May Facilitate Motor Unit Size Expansion to Compensate for Declining Motor Unit Numbers in Older Age (2019)
Journal Article
Piasecki, M., Ireland, A., Piasecki, J., Degens, H., Stashuk, D. W., Swiecicka, A., …McPhee, J. S. (2019). Long-Term Endurance and Power Training May Facilitate Motor Unit Size Expansion to Compensate for Declining Motor Unit Numbers in Older Age. Frontiers in Physiology, 10, Article 449. https://doi.org/10.3389/fphys.2019.00449

© 2019 Frontiers Media S.A. All Rights Reserved. The evidence concerning the effects of exercise in older age on motor unit (MU) numbers, muscle fiber denervation and reinnervation cycles is inconclusive and it remains unknown whether any effects are... Read More about Long-Term Endurance and Power Training May Facilitate Motor Unit Size Expansion to Compensate for Declining Motor Unit Numbers in Older Age.