B. Doleman
Why most published meta-analysis findings are false
Doleman, B.; Williams, J. P.; Lund, J.
Abstract
Almost a decade after the controversial paper ‘why most published research findings are false’ was written [1], we re-visit this concern with regard to published meta-analyses. Although reading the title of this article may make some pause for thought (or vehemently disagree), if you simply subscribe to the findings of Ioannidis’s paper then the logical conclusion is that the meta-analyses of primary studies are equally susceptible to being false. Indeed, it was asserted in the paper that meta-analyses of small, inconclusive studies (very common) are probably false [1]. But how can this be when meta-analyses sit unchallenged at the top of the hierarchy of evidence (despite being retrospective and observational in nature)? We will first examine the evidence for our assertion, and then provide reasons why meta-analyses are poor predictors of results from large trials gained from the authors’ experience in perioperative meta-analyses.
Citation
Doleman, B., Williams, J. P., & Lund, J. (2019). Why most published meta-analysis findings are false. Techniques in Coloproctology, 23(9), 925-928. https://doi.org/10.1007/s10151-019-02020-y
Journal Article Type | Article |
---|---|
Acceptance Date | Jun 17, 2019 |
Online Publication Date | Jun 25, 2019 |
Publication Date | Sep 1, 2019 |
Deposit Date | Jan 6, 2020 |
Journal | Techniques in Coloproctology |
Print ISSN | 1123-6337 |
Electronic ISSN | 1128-045X |
Publisher | Springer Nature |
Peer Reviewed | Not Peer Reviewed |
Volume | 23 |
Issue | 9 |
Pages | 925-928 |
DOI | https://doi.org/10.1007/s10151-019-02020-y |
Keywords | Surgery; Gastroenterology |
Public URL | https://nottingham-repository.worktribe.com/output/3525406 |
Publisher URL | https://link.springer.com/article/10.1007/s10151-019-02020-y |
You might also like
Differences in progression by surgical specialty: A national cohort study
(2022)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: digital-library-support@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search