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Outputs (30)

Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans (2015)
Journal Article

Stable isotope tracer methodologies are becoming increasingly widespread in metabolic research; yet a number of factors restrict their implementation, such as, i.v infusions, multiple cannulae, tissue samples, and significant cost. We recently valida... Read More about Internal comparison between deuterium oxide (D2O) and L-[ring-13C6] phenylalanine for acute measurement of muscle protein synthesis in humans.

Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression (2015)
Journal Article
Gakhar, H., Dhillon, A., Blackwell, J., Hussain, K., Bommireddy, R., Klezl, Z., & Williams, J. (2015). Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression. European Spine Journal, 24(10), 2150-2155. https://doi.org/10.1007/s00586-015-4050-7

Background

Age-related loss of functional muscle mass is associated with reduced functional ability and life expectancy. In disseminated cancer, age-related muscle loss may be exacerbated by cachexia and poor nutritional intake, increasing functio... Read More about Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression.

A prospective study of adverse drug reactions to antiepileptic drugs in children (2015)
Journal Article
Anderson, M., Egunsola, O., Cherrill, J., Millward, C., Fakis, A., & Choonara, I. (2015). A prospective study of adverse drug reactions to antiepileptic drugs in children. BMJ Open, 5, Article e008298. https://doi.org/10.1136/bmjopen-2015-008298

Objectives To prospectively determine the nature and rate of adverse drug reactions (ADRs) in children on antiepileptic drugs (AEDs) and to prospectively evaluate the effect of AEDs on behaviour.

Setting A single centre prospective observational s... Read More about A prospective study of adverse drug reactions to antiepileptic drugs in children.

The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men (2015)
Journal Article
Phillips, B. E., Atherton, P. J., Varadhan, K., Limb, M. C., Wilkinson, D. J., Sjøberg, K. A., …Williams, J. P. (2015). The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men. Journal of Physiology, 593(12), https://doi.org/10.1113/JP270343

The anabolic effects of dietary protein on skeletal muscle depend on adequate skeletal muscle perfusion, which is impaired in older people. This study explores fed state muscle microvascular blood flow, protein metabolism and exercise training status... Read More about The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men.

Provision of NHS generalist and specialist services to care homes in England: review of surveys (2015)
Journal Article
Iliffe, S., Davies, S. L., Gordon, A. L., Schneider, J., Dening, T., Bowman, C., …Goodman, C. (2016). Provision of NHS generalist and specialist services to care homes in England: review of surveys. Primary Health Care Research and Development, 17(2), 122-137. https://doi.org/10.1017/S1463423615000250

Background: The number of beds in care homes (with and without nurses) in the United Kingdom is three times greater than the number of beds in National Health Service (NHS) hospitals. Care homes are predominantly owned by a range of commercial, not-f... Read More about Provision of NHS generalist and specialist services to care homes in England: review of surveys.