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Outputs (34)

Pneumococcal pneumonia trends in adults hospitalised with community-acquired pneumonia over 10 years (2013-2023), and the role of serotype 3 (2024)
Journal Article
Lansbury, L., McKeever, T. M., Lawrence, H., Pick, H., Baskaran, V., Edwards-Pritchard, R. C., Matthews, L., Bailey, H., Ashton, D., Bendall, L., Rodrigo, C., Daniel, P., Litt, D., Eletu, S., Parmar, H., Sheppard, C. L., Ladhani, S., Trotter, C., & Lim, W. S. (in press). Pneumococcal pneumonia trends in adults hospitalised with community-acquired pneumonia over 10 years (2013-2023), and the role of serotype 3. Thorax,

Carriage of Streptococcus pneumoniae in adults hospitalised with community-acquired pneumonia (2024)
Journal Article
Lansbury, L., McKeever, T. M., Lawrence, H., Pick, H., Baskaran, V., Edwards-Pritchard, R. C., Ashton, D., Rodrigo, C., Daniel, P., Litt, D., Eletu, S., Parmar, H., Sheppard, C. L., Ladhani, S., Trotter, C., & Lim, W. S. (2024). Carriage of Streptococcus pneumoniae in adults hospitalised with community-acquired pneumonia. Journal of Infection, 89(5), Article 106277. https://doi.org/10.1016/j.jinf.2024.106277

Objectives

We aimed to determine the prevalence of and risk factors for nasopharyngeal and oral pneumococcal carriage in adults with community-acquired pneumonia (CAP), and the relationship between carried and disease-causing serotypes.

Methods... Read More about Carriage of Streptococcus pneumoniae in adults hospitalised with community-acquired pneumonia.

Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study (2023)
Journal Article
Lansbury, L., Lawrence, H., McKeever, T. M., French, N., Aston, S., Hill, A. T., …Lim, W. S. (2024). Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study. Lancet Regional Health – Europe, 37, Article 100812. https://doi.org/10.1016/j.lanepe.2023.100812

Background: Higher-valency pneumococcal vaccines are anticipated. We aimed to describe serotype distribution and risk factors for vaccine-serotype community-acquired pneumonia (CAP) in the two years pre-SARS-CoV-2 pandemic. Methods: We conducted a pr... Read More about Pneumococcal serotypes and risk factors in adult community-acquired pneumonia 2018–20; a multicentre UK cohort study.

Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores (2022)
Journal Article
Forster, S., McKeever, T. M., Churpek, M., Gonem, S., & Shaw, D. (2022). Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores. Clinical Medicine, 22(5), 409-415. https://doi.org/10.7861/clinmed.2022-0074

Aims Accurately predicting risk of patient deterioration is vital. Altered physiology in chronic disease affects the prognostic ability of vital signs based early warning score systems. We aimed to assess the potential of early warning score patterns... Read More about Predicting outcome in acute respiratory admissions using patterns of National Early Warning Scores.

Impact of Coexisting Dementia on Inpatient Outcomes for Patients Admitted with a COPD Exacerbation (2022)
Journal Article
Gupta, A., McKeever, T. M., Hutchinson, J. P., & Bolton, C. E. (2022). Impact of Coexisting Dementia on Inpatient Outcomes for Patients Admitted with a COPD Exacerbation. International Journal of Chronic Obstructive Pulmonary Disease, 2022(17), 535-544. https://doi.org/10.2147/copd.s345751

Purpose: People with COPD are at a higher risk of cognitive dysfunction than the general population. However, the additional impact of dementia amongst such patients is not well understood, particularly in those admitted with a COPD exacerbation. We... Read More about Impact of Coexisting Dementia on Inpatient Outcomes for Patients Admitted with a COPD Exacerbation.

Co-infection in critically ill patients with COVID-19: an observational cohort study from England (2021)
Journal Article
Baskaran, V., Lawrence, H., Lansbury, L., Webb, K., Safavi, S., Zainuddin, I., …Shen Lim, W. (2021). Co-infection in critically ill patients with COVID-19: an observational cohort study from England. Journal of Medical Microbiology, 70(4), Article 001350. https://doi.org/10.1099/jmm.0.001350

Introduction: During previous viral pandemics, reported co-infection rates and implicated pathogens have varied. In the 1918 influenza pandemic, a large proportion of severe illness and death was complicated by bacterial co-infection, predominantly S... Read More about Co-infection in critically ill patients with COVID-19: an observational cohort study from England.

The feasibility and tolerability of using Inspiratory Muscle Training (IMT) with adults discharged from the hospital with community-acquired pneumonia (CAP) (2021)
Journal Article
Pick, H., Faghy, M., Cresswell, G., Ashton, D., Bolton, C., McKeever, T., …Bewick, T. (2021). The feasibility and tolerability of using Inspiratory Muscle Training (IMT) with adults discharged from the hospital with community-acquired pneumonia (CAP). Advances in Respiratory Medicine, 89, 216-220. https://doi.org/10.5603/ARM.a2021.0002

Background: Patients experience substantial morbidity following discharge from hospital and during recovery from community-acquired pneumonia (CAP). Inspiratory muscle training (IMT) has demonstrated improved functional capacity and reduced patient-r... Read More about The feasibility and tolerability of using Inspiratory Muscle Training (IMT) with adults discharged from the hospital with community-acquired pneumonia (CAP).

Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study (2020)
Journal Article
Lawrence, H., Pick, H., Baskaran, V., Daniel, P., Rodrigo, C., Ashton, D., …Lim, W. S. (2020). Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study. PLoS Medicine, 17(10), Article e1003326. https://doi.org/10.1371/journal.pmed.1003326

Background: Vaccination with the 23-valent pneumococcal polysaccharide vaccine (PPV23) is available in the UK to adults aged 65 years or over and those in defined clinical risk groups. We evaluated the vaccine effectiveness (VE) of PPV23 against vac... Read More about Effectiveness of the 23-valent pneumococcal polysaccharide vaccine against vaccine serotype pneumococcal pneumonia in adults: a case-control test-negative design study.

Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies (2020)
Journal Article
Chalitsios, C. V., Shaw, D. E., & McKeever, T. M. (2020). Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies. Thorax, 76(1), 21-28. https://doi.org/10.1136/thoraxjnl-2020-215664

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Background Inhaled (ICS) and oral (OCS) corticosteroids are used widely in asthma; however, the risk of osteoporosis and fragility fracture (... Read More about Risk of osteoporosis and fragility fractures in asthma due to oral and inhaled corticosteroids: two population-based nested case-control studies.