Outputs (60)

Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood (2015)
Journal Article
Redsell, S. A., Edmonds, B., Swift, J. A., Siriwardena, A. N., Weng, S., Nathan, D., & Glazebrook, C. (2016). Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood. Maternal and Child Nutrition, 12(1), https://doi.org/10.1111/mcn.12184

The risk factors for childhood overweight and obesity are known and can be identified antenatally or during infancy, however, the majority of effective interventions are designed for older children. This review identified interventions designed to re... Read More about Systematic review of randomised controlled trials of interventions that aim to reduce the risk, either directly or indirectly, of overweight and obesity in infancy and early childhood.

Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study (2015)
Journal Article
Otete, H. E., Orton, E., Fleming, K. M., & West, J. (2016). Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study. Liver International, 36(4), 538-546. https://doi.org/10.1111/liv.13002

BACKGROUND & AIMS:
Cirrhosis because of alcohol could be avoided if drinking behaviour could be altered earlier in the disease course. Our aim was to quantify the burden of morbidities in patients prior to alcoholic cirrhosis diagnosis, as this may... Read More about Alcohol-attributable healthcare attendances up to 10 years prior to diagnosis of alcoholic cirrhosis: a population based case-control study.

Pharmacological interventions for promoting smoking cessation during pregnancy (2015)
Journal Article
Coleman, T., Chamberlain, C., Davey, M.-A., Cooper, S., & Leonardi-Bee, J. (2015). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD010078.pub2

Background

Smoking in pregnancy is a public health problem. When used by non-pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion and varenicline) are effective for smoking cessation, however, their efficacy and safet... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.

Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database (2015)
Journal Article
Hill, T., Coupland, C., Morriss, R. K., Arthur, A., Moore, M., & Hippisley-Cox, J. (2015). Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database. BMC Psychiatry, 15, Article 315. https://doi.org/10.1186/s12888-015-0701-9

Background: Epilepsy is a serious condition which can profoundly affect an individual’s life. While there is some evidence to suggest an association between antidepressant use and epilepsy and seizures it is conflicting and not conclusive. Antidepres... Read More about Antidepressant use and risk of epilepsy and seizures in people aged 20 to 64 years: cohort study using a primary care database.

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial (2015)
Journal Article
Hawkey, C. J., Allez, M., Clark, M. M., Labopin, M., Lindsay, J. O., Ricart, E., Rogler, G., Rovira, M., Satsangi, J., Danese, S., Russell, N., Gribben, J., Johnson, P., Larghero, J., Thieblemont, C., Ardizzone, S., Dierickx, D., Ibatici, A., Littlewood, T., Onida, F., …Farge, D. (2015). Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial. Journal of the American Medical Association, 314(23), 2524-2534. https://doi.org/10.1001/jama.2015.16700

Importance: Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease.

Objective: To evaluate the effect of autologous HSCT on refractory Crohn disease.

Design, Setting, and Pa... Read More about Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.

Risk and protective factors for falls on stairs in young children: multicentre case–control study (2015)
Journal Article
Kendrick, D., Zou, K., Ablewhite, J., Watson, M., Coupland, C., Kay, B., Hawkins, A., & Reading, R. (2016). Risk and protective factors for falls on stairs in young children: multicentre case–control study. Archives of Disease in Childhood, 101(10), 909-916. https://doi.org/10.1136/archdischild-2015-308486

Aim: To investigate risk and protective factors for stair falls in children aged <5 years.

Methods: Multicentre case–control study at hospitals, minor injury units and general practices in and around four UK study centres. Cases were children with...

Cycling infrastructure for reducing cycling injuries in cyclists (2015)
Journal Article
Mulvaney, C. A., Smith, S., Watson, M. C., Parkin, J., Coupland, C., Miller, P., Kendrick, D., & McClintock, H. (2015). Cycling infrastructure for reducing cycling injuries in cyclists. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD010415.pub2

Background: Cycling is an attractive form of transport. It is beneficial to the individual as a form of physical activity that may fit more readily into an individual’s daily routine, such as for cycling to work and to the shops, than other physical... Read More about Cycling infrastructure for reducing cycling injuries in cyclists.

Small area synthetic estimates of smoking prevalence during pregnancy in England (2015)
Journal Article
Szatkowski, L., Fahy, S., Coleman, T., Taylor, J., Twigg, L., Moon, G., & Leonardi-Bee, J. (2015). Small area synthetic estimates of smoking prevalence during pregnancy in England. Population Health Metrics, 13(34), https://doi.org/10.1186/s12963-015-0067-8

Background: Complete and accurate data on maternal smoking prevalence during pregnancy are not available at a local geographical scale in England. We employ a synthetic estimation approach to predict the expected prevalence of smoking during pregnanc... Read More about Small area synthetic estimates of smoking prevalence during pregnancy in England.

Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care (2015)
Journal Article
Christie, N., Beckett, K., Earthy, S., Kellezi, B., Sleney, J., Barnes, J., Jones, T., & Kendrick, D. (2016). Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care. British Journal of General Practice, 66(642), e24-e31. https://doi.org/10.3399/bjgp15X688141

Background: In the UK, studies suggest that the transition from hospital to home after an injury can be a difficult time and many patients report feeling inadequately prepared. Patients often use primary care services after hospital discharge. These... Read More about Seeking support after hospitalisation for injury: a nested qualitative study of the role of primary care.

Risk and protective factors for falls on one level in young children: multicentre case-control study (2015)
Journal Article
Benford, P., Young, B., Coupland, C., Watson, M., Hindmarch, P., Hayes, M., Goodenough, T., Majsak-Newman, G., & Kendrick, D. (2015). Risk and protective factors for falls on one level in young children: multicentre case-control study. Injury Prevention, 21(6), https://doi.org/10.1136/injuryprev-2015-041581

Background: Childhood falls are an important global public health problem, but there is a lack of evidence about their prevention. Falls on one level result in considerable morbidity and they are costly to health services.

Objective: To estimate o... Read More about Risk and protective factors for falls on one level in young children: multicentre case-control study.