Regional differences in human biliary tissues and corresponding in vitro derived organoids
(2020)
Journal Article
Rimland, C. A., Tilson, S. G., Morell, C. M., Tomaz, R. A., Lu, W.-Y., Adams, S. E., Georgakopoulos, N., Otaizo-Carrasquero, F., Myers, T. G., Ferdinand, J. R., Gieseck, R. L., Sampaziotis, F., Tysoe, O. C., Wesley, B., Muraro, D., Oniscu, G. C., Hannan, N. R., Forbes, S. J., Saeb-Parsy, K., Wynn, T. A., & Vallier, L. (2021). Regional differences in human biliary tissues and corresponding in vitro derived organoids. Hepatology, 73(1), 247-267. https://doi.org/10.1002/hep.31252
Background
Organoids provide a powerful system to study epithelia in vitro . Recently, this approach was applied successfully to the biliary tree, a series of ductular tissues responsible for the drainage of bile and pancreatic secretions. More prec...
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