Redox Environment, Free Radical, and Oxidative DNA Damage
(2013)
Journal Article
Storr, S. J., Woolston, C. M., Zhang, Y., & Martin, S. G. (2013). Redox Environment, Free Radical, and Oxidative DNA Damage. Antioxidants and Redox Signaling, 18(18), 2399-2408. https://doi.org/10.1089/ars.2012.4920
Outputs (36)
Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas (2013)
Journal Article
Storr, S. J., Pu, X., Davis, J., Lobo, D., Reece-Smith, A. M., Parsons, S. L., Madhusudan, S., & Martin, S. G. (2013). Expression of the calpain system is associated with poor clinical outcome in gastro-oesophageal adenocarcinomas. Journal of Gastroenterology, 48(11), 1213-1221. https://doi.org/10.1007/s00535-012-0743-4
Base Excision Repair, the Redox Environment and Therapeutic Implications (2012)
Journal Article
J. Storr, S., M. Woolston, C., & G. Martin, S. (2012). Base Excision Repair, the Redox Environment and Therapeutic Implications. Current Molecular Pharmacology, 5(1), 88-101. https://doi.org/10.2174/1874467211205010088Control of redox homeostasis is crucial for a number of cellular processes with deregulation leading to a number of serious consequences including oxidative damage such induction of DNA base lesions. The DNA lesions caused by oxidative damage are pri... Read More about Base Excision Repair, the Redox Environment and Therapeutic Implications.
Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer (2011)
Journal Article
Woolston, C. M., Storr, S. J., Ellis, I. O., Morgan, D. A., & Martin, S. G. (2011). Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer. Radiotherapy and Oncology, 100(2), 308-313. https://doi.org/10.1016/j.radonc.2011.05.029Background and purpose
Deregulated redox systems provide cancer cells protection from increased oxidative stress, such as that induced by ionizing radiation. Expression of the thioredoxin system proteins (thioredoxin, thioredoxin reductase and thior... Read More about Expression of thioredoxin system and related peroxiredoxin proteins is associated with clinical outcome in radiotherapy treated early stage breast cancer.
Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy (2011)
Journal Article
Storr, S. J., Woolston, C. M., Barros, F. F., Green, A. R., Shehata, M., Chan, S. Y., Ellis, I. O., & Martin, S. G. (2011). Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy. International Journal of Cancer, 129(7), 1773-1780. https://doi.org/10.1002/ijc.25832The calpain family, and their endogenous inhibitor calpastatin, has been implicated in cancer progression, and recent in vitro data have indicated a role in trastuzumab resistance. The aims of our study were to examine expression levels of calpastati... Read More about Calpain-1 expression is associated with relapse-free survival in breast cancer patients treated with trastuzumab following adjuvant chemotherapy.
Redox Protein Expression Predicts Radiotherapeutic Response in Early-Stage Invasive Breast Cancer Patients (2011)
Journal Article
Woolston, C. M., Al-Attar, A., Ellis, I. O., Storr, S. J., Morgan, D. A., & Martin, S. G. (2011). Redox Protein Expression Predicts Radiotherapeutic Response in Early-Stage Invasive Breast Cancer Patients. International Journal of Radiation Oncology - Biology - Physics, 79(5), 1532-1540. https://doi.org/10.1016/j.ijrobp.2010.11.002Purpose
Early-stage invasive breast cancer patients have commonly undergone breast-conserving surgery and radiotherapy. In a large majority of these patients, the treatment is effective; however, a proportion will develop local recurrence. Deregul... Read More about Redox Protein Expression Predicts Radiotherapeutic Response in Early-Stage Invasive Breast Cancer Patients.