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Outputs (14)

Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer (2015)
Journal Article
Abduljabbar, R., Negm, O. H., Lai, C.-F., Jerjees, D. A., Al-Kaabi, M., Hamed, M. R., …Ellis, I. O. (2015). Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer. Breast Cancer Research and Treatment, 150(2), 335-346. https://doi.org/10.1007/s10549-015-3335-1

The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily of transcription factors, which exerts anti-proliferative and anti-apoptotic activities. The GR is expressed in a large proportion of breast cancer (BC) although levels... Read More about Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer.

AKT and 14-3-3 regulate Notch4 nuclear localization (2015)
Journal Article
Ramakrishnan, G., Davaakhuu, G., Chung, W. C., Zhu, H., Rana, A., Filipovic, A., …Tzivion, G. (2015). AKT and 14-3-3 regulate Notch4 nuclear localization. Scientific Reports, 5(1), Article 8782. https://doi.org/10.1038/srep08782

Members of the Notch family of transmembrane receptors, Notch1-4 in mammals, are involved in the regulation of cell fate decisions and cell proliferation in various organisms. The Notch4 isoform, which is specific to mammals, was originally identifie... Read More about AKT and 14-3-3 regulate Notch4 nuclear localization.