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Outputs (129)

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset? (2021)
Journal Article

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability i... Read More about Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?.

Causal Relationship between the Right Auditory Cortex and Speech-Evoked Envelope-Following Response: Evidence from Combined Transcranial Stimulation and Electroencephalography (2021)
Journal Article
Mai, G., & Howell, P. (2022). Causal Relationship between the Right Auditory Cortex and Speech-Evoked Envelope-Following Response: Evidence from Combined Transcranial Stimulation and Electroencephalography. Cerebral Cortex, 32(7), 1437-1454. https://doi.org/10.1093/cercor/bhab298

Speech-evoked envelope-following response (EFR) reflects brain encoding of speech periodicity that serves as a biomarker for pitch and speech perception and various auditory and language disorders. Although EFR is thought to originate from the subcor... Read More about Causal Relationship between the Right Auditory Cortex and Speech-Evoked Envelope-Following Response: Evidence from Combined Transcranial Stimulation and Electroencephalography.

Redesigning a Web-Based Stakeholder Consensus Meeting About Core Outcomes for Clinical Trials: Formative Feedback Study (2021)
Journal Article
Katiri, R., Hall, D. A., Hoare, D. J., Fackrell, K., Horobin, A., Buggy, N., …Core Rehabilitation Outcome Set For Single-Sided Deafness (CROSSSD) Initiative. (2021). Redesigning a Web-Based Stakeholder Consensus Meeting About Core Outcomes for Clinical Trials: Formative Feedback Study. JMIR Formative Research, 5(8), Article e28878

Background: Clinical trials that assess the benefits and harms of an intervention do so by measuring and reporting outcomes. Inconsistent selection and diversity in the choice of outcomes makes it challenging to directly compare interventions. To ach... Read More about Redesigning a Web-Based Stakeholder Consensus Meeting About Core Outcomes for Clinical Trials: Formative Feedback Study.

Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier (2021)
Journal Article

To investigate whether therapeutic hypothermia augments the restorative impact of protein kinase C-β (PKC-β) and Nox2 inhibition on an in vitro model of human blood–brain barrier (BBB). Cells cultured in normoglycaemic (5.5mM) or hyperglycaemic (25mM... Read More about Therapeutic hypothermia augments the restorative effects of PKC-β and Nox2 inhibition on an in vitro model of human blood–brain barrier.

The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study (2021)
Journal Article
Pearson, S. E., Caimino, C., Shabbir, M., & Baguley, D. M. (2022). The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study. Journal of Cancer Survivorship, 16, 976-987. https://doi.org/10.1007/s11764-021-01089-5

Purpose: This study aimed to explore the burden of inner ear damage (ototoxicity) on adults living with and beyond cancer treated with chemotherapy and the impact on their quality of life (QoL). Furthermore, this study aimed to explore patient awaren... Read More about The impact of chemotherapy-induced inner ear damage on quality of life in cancer survivors: a qualitative study.

Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model (2021)
Journal Article
Plas, M. C. E., Craig, M., Schmid, S., Chappell, M. A., & Osch, M. J. P. (2022). Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model. Magnetic Resonance in Medicine, 87(1), 85-101. https://doi.org/10.1002/mrm.28960

Purpose In this paper, the ability to quantify cerebral blood flow by arterial spin labeling (ASL) was studied by investigating the separation of the macrovascular and tissue component using a 2-component model. Underlying assumptions of this model,... Read More about Validation of the estimation of the macrovascular contribution in multi‐timepoint arterial spin labeling MRI using a 2‐component kinetic model.

Risk Factors, Clinical Outcomes, and Prognostic Factors of Bacterial Keratitis: The Nottingham Infectious Keratitis Study (2021)
Journal Article
Ting, D. S. J., Cairns, J., Gopal, B. P., Shan Ho, C. S., Krstic, L., Elsahn, A., …Dua, H. S. (2021). Risk Factors, Clinical Outcomes, and Prognostic Factors of Bacterial Keratitis: The Nottingham Infectious Keratitis Study. Frontiers in Medicine, 8, Article 715118. https://doi.org/10.3389/fmed.2021.715118

Background/Aim: To examine the risk factors, clinical characteristics, outcomes, and prognostic factors of bacterial keratitis (BK) in Nottingham, UK. Methods: This was a retrospective study of patients who presented to the Queen's Medical Centre, No... Read More about Risk Factors, Clinical Outcomes, and Prognostic Factors of Bacterial Keratitis: The Nottingham Infectious Keratitis Study.

Ratlas-LH: An MRI template of the Lister hooded rat brain with stereotaxic coordinates for neurosurgical implantations (2021)
Journal Article
Prior, M. J., Bast, T., McGarrity, S., Goldschmidt, J., Vincenz, D., Seaton, A., …Pitiot, A. (2021). Ratlas-LH: An MRI template of the Lister hooded rat brain with stereotaxic coordinates for neurosurgical implantations. Brain and Neuroscience Advances, 5,

There is currently no brain atlas available to specifically determine stereotaxic coordinates for neurosurgery in Lister hooded rats despite the popularity of this strain for behavioural neuroscience studies in the UK and elsewhere. We have created a... Read More about Ratlas-LH: An MRI template of the Lister hooded rat brain with stereotaxic coordinates for neurosurgical implantations.

Changes in Orientation Behavior due to Extended High-Frequency (5 to 10 kHz) Spatial Cues (2021)
Journal Article
Whitmer, W. M., McShefferty, D., Levy, S. C., Naylor, G., & Edwards, B. (2022). Changes in Orientation Behavior due to Extended High-Frequency (5 to 10 kHz) Spatial Cues. Ear and Hearing, 43(2), 545-553. https://doi.org/10.1097/AUD.0000000000001113

Objectives: Current hearing aids have a limited bandwidth, which limits the intelligibility and quality of their output, and inhibits their uptake. Recent advances in signal processing, as well as novel methods of transduction, allow for a greater... Read More about Changes in Orientation Behavior due to Extended High-Frequency (5 to 10 kHz) Spatial Cues.