Outputs (42)

Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial (2014)
Journal Article
Pushpa-Rajah, A., Bradshaw, L., Dorling, J., Gyte, G., Mitchell, E. J., Thornton, J., & Duley, L. (2014). Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial. Trials, 15(258), https://doi.org/10.1186/1745-6215-15-258

Background: Preterm birth is the most important single determinant of adverse outcome in the United Kingdom; one in every 70 babies (1.4%) is born before 32 weeks (very preterm), yet these births account for over half of infant deaths.
Deferring cor... Read More about Cord pilot trial - immediate versus deferred cord clamping for very preterm birth (before 32 weeks gestation): study protocol for a randomized controlled trial.

Recommendations for assessing cognitive risks in young children treated for ependymoma for clinical and research protocols: evidence from a systematic literature review (2014)
Journal Article
Morrall, M. C., Pitchford, N. J., Waters, E. C., Ablett, K. L., Stocks, H., Walker, D., & Grundy, R. G. (2014). Recommendations for assessing cognitive risks in young children treated for ependymoma for clinical and research protocols: evidence from a systematic literature review. Journal of Pediatric Oncology Nursing, 2(1), https://doi.org/10.14205/2309-3021.2014.02.01.4

Background: Current treatment approaches for pediatric ependymoma differ between North American and European studies. Post-surgical adjuvant irradiation is used in children aged <36 months in North America, whilst European approaches use chemotherapy...

Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries (2014)
Journal Article
Hernandez Medrano, J., Campbell, B., Onions, V., Pincott-Allen, C., Aljaser, F., Fisher, J., …Picton, H. (2014). Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries. Human Reproduction, 29(8), 1749-1763. https://doi.org/10.1093/humrep/deu144

study question: Is it possible to restore ovarian function and natural fertility following the cryopreservation and autotransplantation of whole ovaries, complete with vascular pedicle, in adult females from a large monovulatory animal model species... Read More about Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries.

EM-010, Gene expression profiling of pediatric ependymomas from the posterior fossa reveals key differences with adult ependymomas (2014)
Presentation / Conference Contribution
Lourdusamy, A., Rogers, H., Rahman, R., Ward, J., & Grundy, R. (2014). EM-010, Gene expression profiling of pediatric ependymomas from the posterior fossa reveals key differences with adult ependymomas. Neuro-Oncology, 16(Suppl_1), i19

BACKGROUND: Ependymoma in children and adults show distinct pathogenesis, biology, and clinical features, it is important to elucidate the transcriptional features that distinguish pediatric ependymomas from adults arising in same anatomical region.... Read More about EM-010, Gene expression profiling of pediatric ependymomas from the posterior fossa reveals key differences with adult ependymomas.

Discrepancies between registration and publication of randomised controlled trials: an observational study (2014)
Journal Article
Walker, K. F., Stevenson, G., & Thornton, J. (2014). Discrepancies between registration and publication of randomised controlled trials: an observational study. Journal of the Royal Society of Medicine, 5(5), https://doi.org/10.1177/2042533313517688

Abstract
OBJECTIVES:
To determine the consistency between information contained in the registration and publication of randomised controlled trials (RCTs).
DESIGN:
An observational study of RCTs published between May 2011 and May 2012 in the Brit... Read More about Discrepancies between registration and publication of randomised controlled trials: an observational study.

European Cystic Fibrosis Society standards of care: best practice guidelines (2014)
Journal Article
Smyth, A. R., Bell, S. C., Bojcin, S., Byron, M., Duff, A., Flume, P., …Wolfe, S. (2014). European Cystic Fibrosis Society standards of care: best practice guidelines. Journal of Cystic Fibrosis, 13(Supp 1), Article S23-S42. https://doi.org/10.1016/j.jcf.2014.03.010

Specialised CF care has led to a dramatic improvement in survival in CF: in the last four decades, well above what was seen in the general population over the same period. With the implementation of newborn screening in many European countries, centr... Read More about European Cystic Fibrosis Society standards of care: best practice guidelines.

Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit (2014)
Journal Article
Smith, C. T., Williamson, P., Jones, A., Smyth, A. R., Hewer, S. L., & Gamble, C. (2014). Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit. Trials, 15(127), https://doi.org/10.1186/1745-6215-15-127

Background
Some level of monitoring is usually required during a clinical trial to protect the rights and safety of trial participants and to safeguard the quality and reliability of trial results. Although there is increasing support for the use of... Read More about Risk-proportionate clinical trial monitoring: an example approach from a non-commercial trials unit.

Processed pseudogenes acquired somatically during cancer development (2014)
Journal Article

Cancer evolves by mutation, with somatic reactivation of retrotransposons being one such mutational process. Germline retrotransposition can cause processed pseudogenes, but whether this occurs somatically has not been evaluated. Here we screen seque... Read More about Processed pseudogenes acquired somatically during cancer development.

Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia? (2014)
Journal Article
Hentchke, M., Caruso, F. B., Paula, L. G., Medeiro, A. K., Gadonski, G., Antonello, I. C., Mistry, H. D., Poli-de-Figueiredo, C., & Pinheiro da Costa, B. (2014). Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia?. Pregnancy Hypertension, 4(2), https://doi.org/10.1016/j.preghy.2014.03.003

Objectives: The purpose of the present study was to evaluate the association between pre-eclampsia and blood groups in a group of pregnant women hospitalized in a University Hospital in Porto Alegre, Brazil -Hospital São Lucas (HSL)/PUCRS.
Study de... Read More about Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia?.

Effects of assisted reproductive technologies on human sex ratio at birth (2014)
Journal Article
Maalouf, W. E., Mincheva, M. N., Campbell, B. K., & Hardy, I. C. (2014). Effects of assisted reproductive technologies on human sex ratio at birth. Fertility and Sterility, 101(5), https://doi.org/10.1016/j.fertnstert.2014.01.041

Objective

To investigate the effect of assisted reproductive technology (ART) treatments on the sex ratio of babies born.
Design

Assessment of direct effects of assisted conception through retrospective data analysis on the progeny sex ratio o... Read More about Effects of assisted reproductive technologies on human sex ratio at birth.