Outputs (2)

Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations (2017)
Journal Article
Fulton, J., Mazumder, B., Whitchurch, J., Monteiro, C. J., Collins, H. M., Chan, C. M., Clemente, M. P., Hernandez Quiles, M., Stewart, E. A., Amoaku, W., Moran, P. M., Mongan, N. P., Persson, J. L., Ali, S., & Heery, D. M. (2017). Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations. Cell Death and Disease, 8, Article e2677. https://doi.org/10.1038/cddis.2017.98

Photoreceptor-specific nuclear receptor (PNR/NR2E3) and Tailless homolog (TLX/NR2E1) are human orthologs of the NR2E group, a subgroup of phylogenetically related members of the Nuclear Receptor (NR) superfamily of transcription factors. We assessed... Read More about Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor (PPARγ) are disrupted by retinal disease-associated mutations.

The envelope gene of transmitted HIV-1 resists a late interferon gamma-induced block (2017)
Journal Article
Rihn, S. J., Foster, T. L., Busnadiego, I., Aziz, M. A., Hughes, J., Neil, S. J. D., & Wilson, S. J. (2017). The envelope gene of transmitted HIV-1 resists a late interferon gamma-induced block. Journal of Virology, 91(7), Article e02254-16. https://doi.org/10.1128/JVI.02254-16

Type I interferon (IFN) signaling engenders an antiviral state that likely plays an important role in constraining HIV-1 transmission and contributes to defining subsequent AIDS pathogenesis. Type II IFN (IFN-γ) also induces an antiviral state but is... Read More about The envelope gene of transmitted HIV-1 resists a late interferon gamma-induced block.