Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites
(2018)
Journal Article
Luderman, K. D., Conroy, J. L., Free, R. B., Southall, N., Ferrer, M., Sanchez-Soto, M., Moritz, A. E., Willette, B. K. A., Fyfe, T. J., Jain, P., Titus, S., Hazelwood, L. A., Aubé, J., Lane, J. R., Frankowski, K. J., & Sibley, D. R. (2018). Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites. Molecular Pharmacology, 94(4), 1197-1209. https://doi.org/10.1124/mol.118.113175
The D1 dopamine receptor is linked to a variety of neuropsychiatric disorders and represents an attractive drug target for the enhancement of cognition in schizophrenia, Alzheimer disease, and other disorders. Positive allosteric modulators (PAMs), w... Read More about Identification of Positive Allosteric Modulators of the D1 Dopamine Receptor That Act at Diverse Binding Sites.